Search for dissertations about: "Dexamethasone and ALL"

Showing result 1 - 5 of 45 swedish dissertations containing the words Dexamethasone and ALL.

  2. 1. Mechanisms of therapy resistance in acute lymphoblastic leukemia

    Author : Kinjal Shah; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALL; B-ALL; T-ALL; dexamethasone; FLT3; Signaling pathways; BCL2; resistance; PLK1; synergy;

    Abstract : Acute lymphoblastic leukemia (ALL) is a highly aggressive pediatric cancer that can affect both B cells and T cells. The advent of new therapies has increased the cure rates for both B-ALL and T-ALL patients. However, some patients still experience relapse with a variable response to the treatment and display poor survival. READ MORE

  4. 2. Diagnosing hyper- and hypocortisolism using saliva samples : pitfalls and how to avoid them

    Author : Nils Bäcklund; Per Dahlqvist; Göran Brattsand; Tommy Olsson; Elisabeth Aardal; Kerstin Landin-Wilhelmsen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cushing s syndrome; Adrenal Insufficiency; Salivary cortisol; Salivary cortisone; Reference intervals; Diagnostic accuracy; Error sources; invärtesmedicin; Internal Medicine; medicinsk biokemi; Medical Biochemistry;

    Abstract : Background: Cushing's syndrome (CS) is caused by high cortisol secretion whereas insufficient cortisol secretion is called adrenal insufficiency (AI). Both are rare diseases with substantial diagnostic delay, and high morbidity and mortality even though effective treatment is available. READ MORE

  5. 3. Anthracyclines : Toxicity and chemotherapy-induced mucositis

    Author : Fredrik Kullenberg; Hans Lennernäs; Erik Sjögren; David Dahlgren; Femke Heindryckx; Henrik Rönnberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthracycline; doxorubicin; idarubicin; toxicity; intracellular concentration; IC50; chemotherapy-induced mucositis; apoptosis; proliferation; permeability; anti-inflammatory drugs; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Anthracyclines belong to a class of cytostatic compounds that are commonly used to treat various types of cancers, including lymphoma, breast cancer and primary liver cancer. The aim of this thesis was to study how two anthracyclines, doxorubicin and idarubicin, induced cytotoxicity in tumor cells, as well as their off-target effect on the gastrointestinal system. READ MORE

  6. 4. Pro- and anti-inflammatory actions in coronary artery disease : with focus on CD56+ T cells and Annexin A1

    Author : Ida Bergström; Lena Jonasson; Eva Särndahl; Jan Ernerudh; Johan Frostegård; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : ¨The atherosclerotic process is considered to be driven by an imbalance between proand anti-inflammatory actions. Still, the inflammatory state in patients with coronary artery disease (CAD) remains to be clarified. READ MORE

  7. 5. Subjective annoyance attributed to electrical equipments and smells - Epidemiology and stress physiology

    Author : Frida Eek; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; environmental intolerance; IEI; epidemiology; diabetology; secreting systems; Endocrinology; cortisol; stress; sekretion; Endokrinologi; Public health; diabetologi; Folkhälsa; epidemiologi; Occupational health; Yrkesmedicin; industrial medicine; arbetsmiljömedicin; Environmental health; Miljömedicin;

    Abstract : Self-reported annoyance from electrical equipment has been in evidence since the mid-eighties, and the first reports of illness from everyday chemicals arose already in the 1960?s. However, the extent of the problem or the mechanisms behind the development of environmentally related annoyance has not yet been fully established. READ MORE