Search for dissertations about: "Dextrans"

Showing result 1 - 5 of 11 swedish dissertations containing the word Dextrans.

  2. 1. FITC-dextrans in neurobiological research

    Author : Dieter Hultström; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. Models for the Transfer of Drugs from the Nasal Cavity to the Central Nervous System

    Author : Björn Jansson; Erik Björk; Sveinbjörn Gizurarson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopharmacy; Administration; intranasal; Nasal mucosa; Central nervous system; Olfactory bulb; Rat; Mouse; Swine; Cattle; Diffusion chambers; culture; In vitro; Biological models; Biological transport; Dextrans; Dopamine; Gels; Polysaccharides; Autoradiography; Fluorescence microscopy; Biofarmaci; Biopharmacy; Biofarmaci;

    Abstract : The blood-brain barrier restricts the access of many compounds, including therapeutic agents, to the brain. Several human studies indicate that nasal administration of hydrophilic compounds, such as peptides, can bypass the blood-brain barrier. The aims of this thesis were to develop and refine models for this direct nose-to-brain transfer. READ MORE

  5. 3. Colloid-osmotic effects in vivo of plasma proteins and dextrans

    Author : Suvit Areekul; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  6. 4. Understanding the gastrointestinal mucus and its impact on drug absorption

    Author : Vicky Barmpatsalou; Christel Bergström; Eva Karlsson; Betty Lomstein Pedersen; Hanne Mørck Nielsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucus; gastrointestinal; pigs; dogs; physiology; colonic; in vitro assay; drug diffusion; macromolecules;

    Abstract : The gastrointestinal mucus is a hydrogel lining the luminal side of the gastrointestinal epithelium. Mucus is vital for gut homeostasis because it protects the epithelium from the noxious external environment. READ MORE

  7. 5. Effects of Macromolecular Crowding on Protein Folding : - in-vitro equilibrium and kinetic studies on selected model systems

    Author : Alexander Christiansen; Pernilla Wittung-Stafshede; Thomas Kiefhaber; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein Folding; macromolecular crowding; excluded volume; spectroscopy; stopped-flow; biokemi; Biochemistry;

    Abstract : Protein folding is the process during which an extended and unstructured polypeptide converts to its compact folded structure that is most often the functional state. The process has been characterized extensively in dilute buffer in-vitro during the last decades but the actual biological place for this process is the inside of living cells. READ MORE