Search for dissertations about: "Diabetic wound"

Showing result 1 - 5 of 24 swedish dissertations containing the words Diabetic wound.

  1. 1. Plasminogen : a novel inflammatory regulator that promotes wound healing

    Author : Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

    Abstract : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. READ MORE

  2. 2. New pathogenic mechanisms in diabetic wound healing

    Author : Vivekananda Sunkari; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Diabetic foot ulcers (DFU) represent one of the most feared and invalidating complication of diabetes with high financial pressure for the healthcare system. For the moment there is no specific therapy available and it has become a priority to develop novel rational therapeutic strategies based on new pathophysiological mechanisms. READ MORE

  3. 3. The Diabetic Foot. Costs, health economic aspects, prevention and quality of life

    Author : Gunnel Ragnarson Tennvall; Socialepidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Social medicine; wound healing; treatment outcome; risk factors; prevention and control; amputation; cost and cost analysis; Socialmedicin; samhällsmedicin;

    Abstract : The overall aims were to investigate the economic consequences of foot complications in diabetic patients, to measure the influence of diabetic foot complications on health-related quality of life (HRQL), and to analyse the cost-effectiveness of interventions to prevent foot ulcers and lower extremity amputations (LEA). The economic consequences of foot ulcers and LEA are large both in a short and a longer perspective. READ MORE

  4. 4. Plasminogen in periodontitis and wound repair

    Author : Rima Sulniute; Tor Ny; Daniel A Lawrence; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The plasminogen activator (PA) system plays a critical role in many physiological and pathological processes, such as fibrinolysis, extracellular matrix (ECM) degradation, wound healing, inflammation, and cancer. The key component of the PA system is plasmin, a broad-spectrum serine protease that is derived from its inactive form, plasminogen. READ MORE

  5. 5. In vitro studies of the diabetic condition using cultured fibroblasts with focus on wound healing

    Author : Karin M. Hehenberger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; diabetes; fibroblasts; wound healing; proliferation; protein kinaseC; lactate; growth factors; resistance.;

    Abstract : This thesis focuses on the diabetic condition at the cellular level, and how thismay lead to late complications. Defect wound healing in diabetic patients is poorlyunderstood, but impaired granulation is observed clinically. We have therefore decidedto study an in vltro system using cultured fibroblasts. READ MORE