Search for dissertations about: "Dicer1 animal model genetics genetic association single nucleotide polymorphism SNP INS-1E AAT FOXP3 beta cell function insulin secretion FFAR1 insulin T2D glucose T1D"

Found 1 swedish dissertation containing the words Dicer1 animal model genetics genetic association single nucleotide polymorphism SNP INS-1E AAT FOXP3 beta cell function insulin secretion FFAR1 insulin T2D glucose T1D.

  2. 1. Beta Cell Function: from Human Genetics to Animal Models

    Author : Martins Kalis; Diabetes - immunovirologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; animal model; Dicer1; genetics; genetic association; single nucleotide polymorphism; SNP; INS-1E; AAT; FOXP3; beta cell function; insulin secretion; FFAR1; insulin; T2D; glucose; T1D;

    Abstract : Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence to abnormal glucose homeostasis. READ MORE