Search for dissertations about: "Dick Wågsäter"

Showing result 1 - 5 of 6 swedish dissertations containing the words Dick Wågsäter.

  2. 1. CXCL16 and CD137 in atherosclerosis

    Author : Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; atherosclerosis; chemokine; cytokine; endothelial cells; inflammation; low-density lipoprotein; macrophages; scavenger receptor; smooth muscle cells; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Abstract : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. READ MORE

  4. 2. Analysis of new biomarkers and their kinetics in connection with ST-elevation myocardial infarction and percutaneous coronary intervention

    Author : Rahel Befekadu Wodajo; Sofia Ramström; Magnus Grenegård; Anders Larsson; Dick Wågsäter; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; STEMI; PTX3; sTNFR1; sTNFR2; Cathepsin S; MASP-1 AT MASP-1 C1-INH; MASP-2 AT; MASP-2 C1-INH;

    Abstract : This thesis studies different biomarkers in a cohort of patients suffering from ST-elevation myocardial infarction (STEMI) who underwent Percutaneous coronary intervention (PCI) in Örebro in 2011-2012. Blood samples were collected at three time points, at the arrival at the hospital, 1-3 days after PCI and for a smaller group of patients also 3 months after PCI. READ MORE

  5. 3. Interrogating Atherosclerotic Plaque Biology Through Responses to Cardiovascular Risk Management and Imaging

    Author : Elin Good; Ebo de Muinck; Petter Dyverfeldt; Tiny Jaarsma; Dick Wågsäter; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Atherosclerosis causes more deaths than any other disease worldwide, and the cause of death is most commonly a rupture of a vulnerable atherosclerotic plaque, resulting in a thrombotic event in the heart or brain. The major risk factors for plaque progression are well known, but all the mechanisms that drive atherosclerotic plaques towards catastrophic events are not yet fully elucidated. READ MORE

  6. 4. Investigation of immune cell-derived factors as potential biomarkers in patients with colorectal cancer

    Author : Levar Shamoun; Dick Wågsäter; Jan Dimberg; Kalle Landerholm; Blanka Kolodziej; Richard Palmqvist; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gene polymorphism; Colorectal cancer; Immunoregulation; Prognosis; Gene and protein expression; Survival; Zmynd15; Genpolymorfism; Kolorektal cancer; Immunreglering; Prognos; Gen- och proteinuttryck; Överlevnad; Zmynd15; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medical Cell Biology; Medicinsk cellbiologi; Patologi; Pathology;

    Abstract : Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related death. It is a heterogeneous disease involving multiple molecular pathways that result in differing phenotypes. Individual variability in CRC susceptibility is influenced by genetic variation, such as single nucleotide polymorphisms (SNPs). READ MORE

  7. 5. Circulating and genetic factors in colorectal cancer : Potential factors for establishing prognosis?

    Author : Renate Slind Olsen; Dick Wågsäter; Roland Andersson; Anita Sjölander; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Colorectal cancer (CRC) is defined as a cancer appearing in the colon or in the rectum. In Sweden, ~ 6300 individuals were diagnosed with the disease in 2014 and ~ 2550 individuals diagnosed with CRC die each year due to their cancer. READ MORE