Search for dissertations about: "Differential gene expression"

Showing result 11 - 15 of 253 swedish dissertations containing the words Differential gene expression.

2. 11. Analysis of RNA and DNA sequencing data : Improved bioinformatics applications

   Author : Benjamín Sigurgeirsson; Joakim Lundeberg; Simon Anders; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Bioteknologi; Biotechnology;

   Abstract : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. READ MORE

4. 12. Subtracted Approaches to Gene Expression Analysis in Atherosclerosis

   Author : Stina Boräng; KTH; []
   Keywords : Representational Difference Analysis; atherosclerosis; gene expression profiling;

   Abstract : Gene expression analysis has evolved as an extensive toolfor elucidation of various biological and molecular eventsoccurring in different organisms. A variety of techniques andsoftware tools have been developed to enable easier and morerapid means of exploring the genetic information. READ MORE

5. 13. Myocardial gene therapy and gene expression in angina pectoris

   Author : Andreas Rück; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Angina pectoris; gene therapy; vascular endothelial growth factor; plasmid; prognosis; collaterals; angiogenesis; gene expression; microarray; natriuretic peptides.;

   Abstract : Background: Angiogenesis does not fully counteract myocardial ischemia in stable angina pectoris. Refractory angina pectoris, with remaining symptoms despite medication and no possibility for bypass surgery or angioplasty, is rather common. Angiogenic gene therapy is a novel treatment strategy for these patients. READ MORE

6. 14. Exploring the Boundaries of Gene Regulatory Network Inference

   Author : Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Abstract : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. READ MORE

7. 15. Analyses of genomic and gene expression signatures

   Author : Rickard Sandberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Microarray; comparative genomics; differential gene expression; cell lines; computational biology;

   Abstract : Biology has entered a challenging, information-intense period where computational experiments are complementing traditional experiments. A plethora of new techniques have allowed biological processes to be investigated on a global scale. READ MORE