Search for dissertations about: "Differential gene expression"

Showing result 16 - 20 of 253 swedish dissertations containing the words Differential gene expression.

  2. 16. Normalization and Differential Gene Expression Analysis of Microarray Data

    Author : Magnus Åstrand; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : DNA microarray technologies have the capability of simultaneously measuring the abundance of thousands of mRNA-sequences. Analysis of microarray data involves many different steps such as image analysis, background correction, and normalization, but also more classical statistical analysis such as testing for significant differences between groups of arrays. READ MORE

  4. 17. Genome-wide Characterization of RNA Expression and Processing

    Author : Ammar Zaghlool; Lars Feuk; Rickard Sandberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA sequencing; RNA splicing; RNA processing; Gene expression; Molekylär genetik; Molecular Genetics;

    Abstract : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. READ MORE

  5. 18. Outcomes of Myosin 1C Gene Expression Depletion on Cancer-related Pathways, in Vitro and in Clinical Samples

    Author : Anna Pfister; Afrouz Behboudi; Sahlgrenska Academy at University of Gothenburg; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MYO1C; myosin 1C; gene expression; pathway analysis; endometrial carcinoma;

    Abstract : The unconventional myosin IC has previously been suggested to be a haploinsufficient tumour suppressor. The mechanism for this action has hitherto been unknown, however, and hence we decided to attempt to elucidate the genes involved. READ MORE

  6. 19. Aspects of Gene Expression Profiling in Disease and Health

    Author : Julia Bergman; Fredrik Pontén; Lars Akslen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; biomarkers; differential diagnostics; immunohistochemistry; transcriptomics; protein profiling; adrenal gland.; Pathology; Patologi;

    Abstract : The aim of this thesis is to in various ways explore protein expression in human normal tissue and in cancer and to apply that knowledge in biomarker discovery.In Paper I the prognostic significance of RNA-binding motif protein 3 (RBM3) is explored in malignant melanoma. READ MORE

  7. 20. Gene Expression in the Brains of Two Lines of Chicken Divergently Selected for High and Low Body Weight

    Author : Sojeong Ka; Finn Hallböök; Tom Porter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chicken; juvenile body weight; divergent selection; gene expression; DNA microarray; quantitiative RT-PCR; hypothalamus; neural plasticity; melanocortin system; endogenous retrovirus; carnitine palmitoyltransferase-1b; Neurobiology; Neurobiologi; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Abstract : Artificial divergent selection of chickens for high and low body weight at 8 weeks of age has produced two lines: the high (HWS) and low (LWS) body weight chicken lines. In addition to the difference in body weight, the lines show extreme differences in feeding behaviour and body composition. READ MORE