Search for dissertations about: "Differential gene expression"

Showing result 21 - 25 of 253 swedish dissertations containing the words Differential gene expression.

  1. 21. Gene expression profiling in animal models of alcoholism

    Author : Christina Arlinde; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alcoholism; gene expression; microarray; animal model; rat; brain;

    Abstract : Genetic and environmental factors in alcoholism interact at the level of the transcriptome to encode the phenotypic traits of this complex clinical syndrome. Because of this, the prospect of simultaneous, genome wide, high-throughput analysis of gene expression in key brain areas potentially offers a novel strategy to identify new molecular treatment targets in this disease. READ MORE

  2. 22. Evolutionary Genomics of Nematode-Trapping Fungi

    Author : Tejashwari Meerupati; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nematode-trapping fungi; Comparative Genomics; Comparative Transcriptomics; Differential gene expression; Gene duplication; Parasitism; Protein family expansion.;

    Abstract : Nematode-trapping fungi are ubiquitous, soil-living organisms with the ability to infect and kill nematodes. These fungi have developed specialized infection structures for the capture of nematodes. READ MORE

  3. 23. The art of transcriptome reconstruction : with applications in Picea abies (L.) H. Karst

    Author : Karl Johan Westrin; Olof Emanuelsson; Henric Zazzi; Lukas Käll; Jens Sundström; Jarkko Salojärvi; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transcriptome reconstruction; transcriptome assembly; transcript isoform detection; Picea abies; acrocona; cone setting; differential expression; gene families; miRNA; quality assessment; transkriptomrekonstruktion; sammansättning av transkriptom; detektering av transkriptisoform; rödgran; kottegran; kottsättning; differentiellt uttryck; genfamiljer; kvalitetsutvärdering; miRNA; Biotechnology; Bioteknologi;

    Abstract : Transcriptome reconstruction is an important component in the bioinformatical part of transcriptome studies. When a reference genome is missing, highly fragmented or incomplete, a de novo transcriptome assembly is the transcriptome reconstruction approach of choice, since in such situations, a simple alignment (or mapping) would not necessarily give all theinformation concerning splice junctions, isoforms or even the full extent of the gene. READ MORE

  4. 24. Biochemical and Physiological Characterization of Nonsymbiotic Plant Hemoglobins

    Author : Nélida Leiva; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hemoglobin; Non-symbiotic hemoglobin; Sugar beet; Ligand binding; Nitric oxide; Gene expression; Gene overexpression; Poplar; Arabidopsis; Lepidium campestre.;

    Abstract : Hemoglobins (Hb) are usually associated with blood in humans. However, these proteins are widely distributed among living organisms. In plants the most known group are the leghemoglobins. Still, other Hbs that not participate in symbiosis are also found. READ MORE

  5. 25. Gene and Protein Expression in Human Gliomas

    Author : Oscar Persson; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumour associated antigen; immunotherapy; glioma; targeted therapy; microarray; proteomics;

    Abstract : The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. READ MORE