Search for dissertations about: "Digital Marketing PhD thesis"

Found 3 swedish dissertations containing the words Digital Marketing PhD thesis.

  2. 1. Longitudinal Models for Quantifying Disease and Therapeutic Response in Multiple Sclerosis

    Author : Ana M. Novakovic; Mats O. Karlsson; Etienne Pigeolet; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonlinear mixed-effects models; pharmacometrics; NONMEM; multiple sclerosis; cladribine; EDSS; item response theory; relapse rate; absolute lymphocyte count; total volume T2 lesions; burden of disease; power; sample size; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Treatment of patients with multiple sclerosis (MS) and development of new therapies have been challenging due to the disease complexity and slow progression, and the limited sensitivity of available clinical outcomes. Modeling and simulation has become an increasingly important component in drug development and in post-marketing optimization of use of medication. READ MORE

  4. 2. Experiencing sense of place in a virtual environment : real in the moment?

    Author : Ingvar Tjøstheim; Rikard Harr; John Waterworth; Phil Turner; Umeå universitet; []
    Keywords : SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; telepresence; perception; sense of place; virtual tourism; video-games; digital humaniora; digital humanities;

    Abstract : The main goal of this thesis is to contribute to telepresence research by investigating a sightseeing experience in a virtual environment (VE) and by discussing insights from theories of telepresence, perception, experience of place, marketing and philosophy. The empirical work concerns a sightseeing experience, a visit to a city in a videogame (the VE). READ MORE

  5. 3. Model-Based Optimization of Clinical Trial Designs

    Author : Camille Vong; Mats O. Karlsson; Andrew C. Hooker; Lena E. Friberg; Marylore Chenel; Oliver Sander; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonlinear mixed-effects models; pharmacometrics; likelihood ratio test; NONMEM; power; sample size; study design; proof-of-concept; dose-finding; population optimal design; LOQ; BQL data; neutropenia; docetaxel; myelosuppression; thrombocytopenia; MTD; Bayesian methods; 3 3 algorithm; dose escalation study; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : General attrition rates in drug development pipeline have been recognized as a necessity to shift gears towards new methodologies that allow earlier and correct decisions, and the optimal use of all information accrued throughout the process. The quantitative science of pharmacometrics using pharmacokinetic-pharmacodynamic models was identified as one of the strategies core to this renaissance. READ MORE