Search for dissertations about: "Dimers"

Showing result 21 - 25 of 169 swedish dissertations containing the word Dimers.

  2. 21. Structure of Small Icosahedral Viruses

    Author : Pavel Plevka; Lars Liljas; Kaspars Tars; Michael Chapman; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; biologi; med inriktning mot strukturbiologi; Biology; with specialization in structural biology;

    Abstract : This thesis presents structural studies on the plant virus Ryegrass mottle virus (RGMoV), the bacteriophage φCb5, and the icosahedral particles and octahedral crystal assembly of a bacteriophage MS2 coat protein mutant. In contrast to other sobemoviruses, the RGMoV coat protein is missing several residues in two of the loop regions important for capsid assembly. READ MORE

  4. 22. p53 Alterations in Human Skin : A Molecular Study Based on Morphology

    Author : Ling Gao; Christer Bush Bush; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; p53; skin; mutation; carcinogenesis; microdissection; UV; Basal cell cancer BCC ; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Mutation of the p53 gene appears to be an early event in skin cancer development. The present study is based on morphology and represents a cellular and genetic investigation of p53 alterations in normal human skin and basal cell cancer. READ MORE

  5. 23. Chromatin Structure: Nucleosome Formation and Positioning

    Author : Hans R. Widlund; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; centromere; formation; chromatin; nucleosome; telomere;

    Abstract : In all eukaryotic cells the DNA is complexed with a group of highly basic histone proteins forming nucleosomes and higher order chromatin structures. In the nucleosome the DNA is tightly wrapped, almost two turns, around an octamer of histone proteins. READ MORE

  6. 24. Macrocyclic Carbohydrate/Amino Acid Hybrid Molecules - Synthesis and Evaluation as Artificial Receptors

    Author : Johan Billing; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 3-dipolar cycloaddition; 3-triazoles; 2; 1; molecular recognition; artificial receptors; sugar amino acids; cyclic peptides; macrocycles; Organic chemistry; Organisk kemi;

    Abstract : Methods were developed for the synthesis of three different types of macrocyclic carbohydrate/amino acid hybrid molecules. In the synthesis of the first type of macrocycles, a glucosamine derivative was oxidized at C6 and the obtained sugar amino acid was coupled to tripeptides. READ MORE

  7. 25. Protein unfolding by interfaces and interactions between polycyclic aromatic hydrocarbons

    Author : Svetla Chakarova Käck; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; first-principles calculations; PAH; denaturation; protein-interface interactions; van der Waals interactions; lattice models; polycyclic aromatic hydrocarbons; DFT; density functional theory;

    Abstract : In order to theoretically study large and complex systems, a variety of approaches that can be categorized loosely as top-down or bottom-up are followed. While our vision is to bridge the gap between these approaches and use them together in multiscale materials modeling, the present thesis is limited to give examples of each type of approach in the study of soft-matter systems. READ MORE