Search for dissertations about: "Dipolar Cycloaddition"
Showing result 1 - 5 of 13 swedish dissertations containing the words Dipolar Cycloaddition.
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1. Synthesis of Nitrogen Heterocycles via 1,3-Dipolar Cycloadditions - Method Development and Applications
Abstract : Because of the diverse properties displayed by nitrogen heterocycles, they are one of the most commonly used structural elements in drug discovery. Due to this variation in properties, however, the chemistry and synthetic pathway to each heterocycle is unique. READ MORE
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2. Perfluroaryl azides : Reactivities, Unique Reactions and their Applications in the Synthesis of Theranostic Agents
Abstract : The work centersaround perfluoroaryl azides (PFAAs), and theirability to undergo certain fast and robusttransformations. The chemistry was furtherappliedfor biomedical applications.The first section focuses on the azide-aldehyde-amine cycloaddition using PFAAs. READ MORE
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3. Stereoselective Nucleophilic Additions to Aldehydes and Synthesis of α-Amino-β- Hydroxy-Esters
Abstract : This thesis deals with the development of new reaction methodology as well as stereochemical investigations. The first part concerns the investigation of 1,2- and merged 1,2- and 1,3- asymmetric induction in Mukaiyama aldol additions to α-heteroatom and α,β- heteroatom substituted aldehydes respectively. READ MORE
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4. Asymmetric 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides, Thiocarbonyl Ylides, and Nitrones
Abstract : This thesis describes the development of methods for thepreparation of chiral non-racemic substituted pyrrolidines,tetrahydrothiophenes, and isoxazolidines. This has beenaccomplished by using asymmetric intermolecular 1,3-dipolarcycloaddition reactions of azomethine ylides, thiocarbonylylides and nitrones, respectively, with variousdipolarophiles. READ MORE
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5. Amino Aacohols : stereoselective synthesis and applications in diversity-oriented synthesis
Abstract : This thesis is divided into three separate parts with amino alcohols as the common feature. The first part describes the development of a novel three-component approach to the synthesis of α-hydroxy-β-amino esters. READ MORE