Search for dissertations about: "Disease Models"

Showing result 21 - 25 of 1335 swedish dissertations containing the words Disease Models.

  2. 21. Heart and lung function - in health and disease : methodological studies in clinical physiology

    Author : Sofia Erelund; Nina Sundström; Urban Wiklund; Sandra Arvidsson; Bengt Johansson; Carl-Johan Carlhäll; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical physiology; reference materials; ECG; dynamic spirometry; HRV; rheumatoid arthritis; cardiovascular disease; ischemic heart disease; Clinical Physiology; klinisk fysiologi;

    Abstract : The human heart and lungs constitute an intricate and dynamic system. Various clinical physiological examinations can be used to evaluate cardio-pulmonary function and identify abnormalities. Thus, it is important to understand how normal physiology presents, to be able to identify pathological findings. READ MORE

  4. 22. Models of alveolar remodeling in chronic lung disease

    Author : Oskar Rosmark; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix ECM ; Decellularization; Mass Spectrometry MS ; Biomechanics; Chronic obstructive pulmonary disease COPD ; Idiopathic pulmonary fibrosis IPF ; Alveolar epithelial cells; Fibroblasts; Lung slices;

    Abstract : Lung function is highly dependent on the structure of the lung parenchyma. Remodeling of the alveolar compartment is a central part of the pathology of chronic lung disease such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). READ MORE

  5. 23. Stem cell-based models to study cellular alterations in Parkinson’s Disease

    Author : Margarita Chumarina; Stamcellslaboratoriet för sjukdomsmodellering i det centrala nervsystemet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; stem cells; IPSCs; dopaminergic neurons; oligodendrocytes; omics;

    Abstract : Parkinson’s Disease (PD) is the most prevalent neurodegenerative movement disorder. Despite investigative efforts into the pathogenesis of the disease, the aetiology and mechanism of PD remains unknown, with multiple factors and cellular pathways known to play a part. READ MORE

  6. 24. Effects of dopamine and excitotoxicity in experimental models of Huntington's disease

    Author : Åsa Petersén; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; excitotoxicity; dopamine; Huntington s disease; striatum; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by an expansion of a CAG repeat in the HD gene, that leads to dysfunction and death of striatal neurons. The pathogenetic mechanisms underlying HD are not known, but excitotoxicity and dopamine (DA) have been suggested to play a role. READ MORE

  7. 25. Involvement of endosomal and synaptic Aβ in models of Alzheimer's disease

    Author : Katarina Willén; Experimentell demensforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Amyloid; Multivesicular body; APP;

    Abstract : .... READ MORE