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Showing result 1 - 5 of 97 swedish dissertations matching the above criteria.

2. 1. New Diagnostic and Therapeutic Approaches in Adrenocortical Cancer

   Author : Tanweera Shaheena Khan; Barbro Eriksson; Mats Bergström; Anna-Lena Hulting; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Adrenocortical cancer; Positron Emission Tomography; Metomidate; Combination chemotherapy; Streptozocin; op -DDD; OPEC; Disease-free Interval; Survival; Responses; Side effects; Receptor protein-tyrosine kinases; c-Kit; Phospho-c-Kit; PDGFRβ; Mutation; Imatinib; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Abstract : Adrenocortical cancer (ACC) is a rare disease that is often difficult to diagnose, and therefore often presents at an advanced stage. Various cytotoxic treatments have been tried with little success. Evaluation of new diagnostic methods and improvement of medical therapies are therefore crucial. READ MORE

4. 2. Leucine-rich repeats and immunoglobulin-like domain (LRIG) proteins : possible prognostic markers in vulvar squamous cell carcinoma, endometrial carcinoma, and oropharymgeal squamous cell carcinoma

   Author : Husam Oda; David Lindquist; Eva Lundin; Ulrika Ottander; Kristina Stefansson; Kate Cuschieri; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vulvar squamous cell carcinoma; endometrial carcinoma; oropharyngeal squamous cell carcinoma; LRIG1-3; HPV; LMO7; HPV-driven; non-HPV-driven; prognosis; overall survival; disease-free survival; p53; Ki-67; CD8 TILs; CD44.; Pathology; patologi;

   Abstract : The human leucine-rich repeats and immunoglobulin-like domain (LRIG) gene family comprises three genes, LRIG1, LRIG2 and LRIG3, which encode the LRIG1, LRIG2 and LRIG3 proteins, respectively. Previous stidies have revealed the different prognostic roles of these proteins in different cancers, and it has been shown that LRIG1 functions as a tumour suppressor in certain cancers via its negative regulation of several receptor tyrosine kinases. READ MORE

5. 3. Cervical and vaginal cancer - aspects on risk factors, prevention and treatment

   Author : Emilia Alfonzo; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical cancer; screening; medical fee; hysterectomy; vaginal cancer; colposcopy; robotic radical hysterectomy; disease-free survival; radical hysterectomy; overall survival;

   Abstract : Background: Participation in screening is associated with a major risk reduction in cervical cancer, but there is a lack of knowledge on whether the cost to the individual has an effect on the participation rate. Women with abnormal findings at screenings are referred for colposcopy. READ MORE

6. 4. Epidural Analgesia for Colorectal Cancer Surgery : Experimental and Clinical studies

   Author : Wiebke Falk; Anil Gupta; Peter Matthiessen; Hans Hjelmqvist; Jonas Åkeson; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; epidural analgesia; local anaesthetics; colon cancer cells; inflammation; postoperative complications; pain; recurrence; disease-free survival; mortality;

   Abstract : Epidural analgesia (EA) with local anaesthetics and opioids is used for pain management after colorectal cancer (CRC) surgery. In recent years, a possible beneficial effect of EA on cancer recurrence and survival after surgery has been proposed. READ MORE

7. 5. Centralized Ovarian Cancer Care - Complications, Costs and Survival

   Author : Charlotte Palmqvist; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian cancer; Survival; Centralization; Surgery; Cytoreduction; Residual disease; Postoperative complications; Cost of illness; Direct costs; Indirect cost; Epidemiology;

   Abstract : Background: Ovarian cancer is often diagnosed at advanced stages, and its mortality is high. Surgical treatment of advanced ovarian cancer strives toward complex primary debulking surgery (PDS), aiming for complete cytoreduction (R0) and improved survival. READ MORE