Search for dissertations about: "Diseases in Twins"
Showing result 1 - 5 of 27 swedish dissertations containing the words Diseases in Twins.
-
1. Digital Twins : High Resolution Disease Models for Optimized Diagnosis and Treatment
Abstract : To study immune-mediated diseases, which can affect the expression of thousands of genes among many different cell types and organs, is a daunting challenge. However, for effective diagnosis and therapeutic treatment it is relevant to understand the regulatory functions of disease. READ MORE
-
2. Complement-mediated kidney diseases: Genotype, phenotype and inhibition studies
Abstract : Complement-mediated kidney diseases are ultrarare conditions characterized by excess complement activation related in most cases to complement gene variants or circulating autoantibodies. These conditions are chronic and can lead to kidney failure. READ MORE
-
3. Epidemiological studies on comorbidity, heritability and co-aggregation in organ-specific autoimmune diseases
Abstract : Autoimmunity is caused by loss of tolerance, whereby the immune system fails to distinguish self from non-self. The autoimmune panorama entails more than 100 diseases that collectively affect close to 5% of the total population, with a higher prevalence in women than in men. READ MORE
-
4. Comparative sequencing of candidate genes in complex disease
Abstract : Complex multi-factorial diseases such as cardiovascular, metabolic, neurological and respiratory disorders affect a great number of people across the world. In the post-Human Genome Sequencing era, genome wide association studies are increasingly viable alternatives to linkage approaches in locating disease genes. READ MORE
-
5. Socioeconomic inequalities in musculoskeletal disorders outcomes and care. Educational inequalities in fracture-related mortality and osteoarthritis
Abstract : Musculoskeletal disorders (MSDs) are a major cause of disability worldwide, and two conditions that are major contributors to the overall burden of MSDs are fractures and osteoarthritis (OA). The Swedish Health and Medical Services Act (HSL 2017:30) states that the goal of all health care services is good health and health care on equal terms for the entire population. READ MORE