Search for dissertations about: "Disorder-to-order transition"
Found 3 swedish dissertations containing the words Disorder-to-order transition.
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1. Biophysical characterization of protein-protein interactions involving intrinsically disordered proteins
Abstract : Intrinsically disordered proteins and regions (IDPs/Rs) are proteins that do not form stable and well-defined structures in their free states but rather occupy an ensemble of conformations that change over time while still staying functional. They are prevalent in the eukaryotic proteome and are involved in various vital processes in the cell where they often interact with their binding partners through coupled binding and folding reactions. READ MORE
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2. Regulation of the multi-functional protein YscU in assembly of the Yersinia type III secretion injectisome
Abstract : Yersinia pseudotuberculosis is a Gram-negative zoonotic pathogenic bacterium causing gastroenteritis in human and animals. It shares a conserved virulence plasmid encoding for a needle-like secretion machinery, or type III secretion system, which can be found in other pathogenic Gram-negative bacteria. READ MORE
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3. Characterization and Engineering of Protein-Protein Interactions Involving PDZ Domains
Abstract : The work presented in this thesis has contributed with knowledge to several aspects of protein-protein interaction involving PDZ domains. A substantial amount of our proteome contains regions that are intrinsically disordered but fold upon ligand interaction. READ MORE
