Search for dissertations about: "Disposition index"

Found 3 swedish dissertations containing the words Disposition index.

  2. 1. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity

    Author : Devjit Tripathy; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Calpain 10 gene; genetics of type 2 diabetes; MODY; Endogenous glucose production; Disposition index; Botnia clamp; IGT; IFG; HOMA; insulin sensitivity; insulin secretion;

    Abstract : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. READ MORE

  4. 2. Endocrine aspects of obesity and weight reduction by bariatric surgery : with special emphasis on beta cell function

    Author : Marie Guldstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Obesity; weight reduction; b ariatric surgery; insulin; glucagon; type 2 diabetes; insulin sensitivity; HPA axis; autonomic nervous system ANS ; cognitive functions; proinsulin; GIP; GLP-1; IGFBP- 1; diazoxide;

    Abstract : Severe obesity is the most predictive acquired risk factor for the development of type 2 diabetes. Bariatric surgery induces marked weight loss and reverses the diabetic state significantly. READ MORE

  5. 3. Insulin resistance in children and adolescents : mechanisms and clinical effects

    Author : Anna E Ek; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Insulin resistance is a condition in which insulin does not achieve appropriate response in different target tissues, it is associated with obesity and one of the main culprits in the development of type 2 diabetes. An early sign of disturbed glucose-insulin homeostasis is impaired fasting glucose (IFG) where glucose is elevated in the fasting state. READ MORE