Search for dissertations about: "Distant Metastasis"

Showing result 1 - 5 of 53 swedish dissertations containing the words Distant Metastasis.

2. 1. Renal cell carcinoma : factors of importance for follow-up and survival

   Author : Farhood Iranparvar Alamdari; Börje Ljungberg; Torgny Rasmuson; Sven Lundstam; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal cell carcinoma; follow-up; VEGFR-1; PS; ESR; stage; prognosis; metastasis; surveillance; TNM classification; adrenalectomy; angiogenesis; VEGF; Urology and andrology; Urologi och andrologi;

   Abstract : Background: Renal cell carcinoma (RCC) is most lethal of the urological cancers, with more than 40% dying of the disease. About 30% of the patients have metastases at initial diagnosis and up to 40% undergoing nephrectomy for localized RCC develop metastasis. READ MORE

4. 2. Invasive and Metastatic Properties of Advanced Prostate Cancer

   Author : Karin Jennbacken; Göteborgs universitet; []
   Keywords : Prostate cancer; Androgen-independent; Castration-resistant; Metastasis; Invasion; Lymphangiogenesis; Cell adhesion; N-cadherin; VEGF-C; MRI;

   Abstract : Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over time an androgen-independent (AI) tumor relapses, which is generally highly aggressive and metastatic. READ MORE

5. 3. Interval cancers, positive predictive value for malignance and other early quality indicators in mammographic screening for breast cancer

   Author : Bedrich Vitak; Ingvar Andersson; Linköpings universitet; []
   Keywords : Mammography; Breast neoplasm; Breast cancer screening; Interval breast cancer; Metastasis; Mortality; MEDICINE; MEDICIN;

   Abstract : The study was designed to evaluate early quality indicators in screening for breast cancer. lt comprised, (i) investigations of compliance, recall, referral, cancer detection, and interval cancer rates in the Östergötland screening programme of women aged 40-74 years; (ii) evaluation of the three-stage diagnostic procedure for pre-operative assessment of women with suspicious mammographic findings; (iii) comprehensive analysis of all invasive interval cancers detected; and (iv) investigation into how to reduce the number of interval cancers without a concomitant increase in false positives. READ MORE

6. 4. The Role of SOX9 in Medulloblastoma

   Author : Vasil Savov; Fredrik Swartling; Ulrich Schüller; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medulloblastoma; SOX9; MYCN; cancer development; recurrence; regulation; tumor metastasis; migration; Medical Science; Medicinsk vetenskap;

   Abstract : Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Overall survival is about 70% and in cases where current treatment fails, the disease recurs and most often is fatal. At the molecular level, MB can be divided into four defined subgroups: WNT, SHH, Group 3 and Group 4. READ MORE

7. 5. Targeted therapeutic strategies for prostate cancer treatment using novel lipid kinase inhibitors in combination with current drugs

   Author : Julius Semenas; Jenny L. Persson; Anna Berghard; Maria Fällman; Thomas Grundström; Lukas Kenner; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; bone metastasis; castration-resistant; treatment; precision therapy; PIP5K1A; steroid hormone receptors; cancer stem cells; Oncology; onkologi;

   Abstract : Prostate cancer (PCa) is one of the most common cancer types and the fifth cancer-related cause of death among Western world men.  The sex steroid hormone, androgen and androgen receptor (AR) play important roles in PCa progression. READ MORE