Search for dissertations about: "Dog"

Showing result 11 - 15 of 201 swedish dissertations containing the word Dog.

  2. 11. Characterizing the spectrum of somatic alterations in canine and human cancers

    Author : Sharadha Sakthikumar; Kerstin Lindblad-Toh; Richard Rosenquist Brandell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dog; osteosarcoma; hemangiosarcoma; glioblastoma; non-coding; whole-exome; whole-genome; sequencing; bioinformatics; comparative genetics.;

    Abstract : Cancers arise as a result of deleterious somatic alterations accumulating in the genome during the process of cell division. These alterations arise either via exposure to mutagens or due to errors occurring during DNA replication. READ MORE

  4. 12. Complex Trait Genetics : Beyond Additivity

    Author : Simon Forsberg; Örjan Carlborg; Julien Ayroles; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; genetic interactions; epistasis; additivity; GWAS; vGWAS; Genetic mapping; yeast; Arabidopsis Thaliana; dog; Genetik; Genetics;

    Abstract : The link between the genotype and the phenotype of an organism is immensely complex. Despite this it can, to a great extent, be captured using models that assume that gene variants combine their effects in an additive manner. This thesis explores aspects of genetics that cannot be fully captured using such additive models. READ MORE

  5. 13. More or Less IgE : Therapeutic Vaccines, Adjuvants and Genes and Their Effect on IgE Levels

    Author : Anna Ledin; Lars Hellman; Kjell-Olov Grönvik; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; IgE; Immunoglobulin; Atopic allergy; Vaccine; Adjuvant; Dog; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Immunoglobulin E (IgE) is an important mediator in atopic allergies. This thesis describes the development of a therapeutic vaccine against IgE and its effects in rats and dogs. The development of an assay to determine IgE levels in dogs, and the finding of a chromosome region in rats that affects IgE levels are also reported. READ MORE

  6. 14. Animal husbandry in the Viking Age town of Birka and its hinterland : excavations in the black earth 1990-95

    Author : Bengt Wigh; Anne Karin Hufthammer; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; animal husbandry; domestication; Viking Age; Birka; cattle; pig; sheep; horse; dog; cat; fur trade; Boskapsskötsel; Kreaturshandel; Uppland; Birka; vikingatiden; Osteologi; historisk osteologi; Historical Osteology;

    Abstract : The Birka Excavations 1990-95 provided a unique opportunity to excavate a Swedish Viking Age town stratigraphically, allowing the finds - including extensive and well-preserved faunal remains - to be dated accurately. This in turn has given the opportunity to study the nature and development of Viking Age animal husbandry in a new, closer perspective. READ MORE

  7. 15. Functional Studies of the Neuropeptide Y System : Receptor-Ligand Interaction and Regulation of Food Intake

    Author : Helena Åkerberg; Dan Larhammar; Rickard Malmström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropeptide Y; G-protein coupled receptor GPCR ; site-directed mutagenesis; pancreatic polypeptide; food intake; dog; Pharmacology; Farmakologi;

    Abstract : The members of the mammalian neuropeptide Y family, i.e. the peptides neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP), are all involved in regulation of food intake. In human and most other mammals they act via receptors Y1, Y2, Y4 and Y5. READ MORE