Search for dissertations about: "Dominic M. Desiderio"

Found 2 swedish dissertations containing the words Dominic M. Desiderio.

  2. 1. Advances for Biomarker Discovery in Neuroproteomics using Mass Spectrometry : From Method Development to Clinical Application

    Author : Marcus O.D. Sjödin; Magnus Wetterhall; Jonas Bergquist; Dominic M. Desiderio; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Biomarker; Proteomics; Central Nervous System; Cerebrospinal Fluid; Traumatic Brain Injury; Cloud-Point Extraction; Neuroproteomics; Relative Quantification; Spinal Cord Stimulation; Neuropathic Pain; Analytical Chemistry; Analytisk kemi;

    Abstract : Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used as biomarkers for early diagnosis, assessing treatment or drug development. Clinical proteomics aim to screen for protein biomarkers by a comprehensive analysis of all proteins expressed in a biological matrix during a certain pathology. READ MORE

  4. 2. Electrifying the Molecules of Life : Peptide and Protein Analysis by Capillary Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry

    Author : Magnus Wetterhall; Jonas Bergquist; Karin E. Markides; Dominic M. Desiderio; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Capillary electrophoresis CE ; Electrospray ionization ESI ; Mass spectrometry MS ; Peptides; Proteins; Cerebrospinal fluid CSF ; Graphite coating; Monomer coating; Polymer coating; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : This thesis describes the current status and novel aspects of the analysis of the molecules of life, i.e. peptides and proteins, using capillary electrophoresis (CE) coupled to mass spectrometry (MS) via (sheathless) electrospray ionization (ESI). Early reports of sheathless CE-ESI-MS were plagued by limited lifetimes of the electrospray emitter. READ MORE