Search for dissertations about: "Dopa"

Showing result 1 - 5 of 93 swedish dissertations containing the word Dopa.

  2. 1. Thiol-Ene CHemistry and Dopa-Functional Materials towards Biomedical Applications

    Author : Kristina Olofsson; Anders Hult; Michael Malkoch; Anders Daugaard; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Thiol-ene chemistry; DOPA; biomedical; UV; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Thiol-ene chemistry is versatile and efficient and can be used as a powerful tool in polymer synthesis. In this thesis, the concept of thiol-ene chemistry has been central, where it has been explored as a tool for the synthesis of well-defined hydrogels and dopa-functional materials towards biomedical applications; such as hydrogels, primers for adhesive fixation of bone fractures, self-healing gels, and micelles for drug-delivery. READ MORE

  4. 2. On dopamine neurons : nerve fiber outgrowth and L-DOPA effects

    Author : Sara af Bjerkén; Ingrid Strömberg; Kathy Steece-Collier; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; GDNF; L-DOPA; L-DOPA induced dyskinesia; Neurobiology; Neurobiologi;

    Abstract : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. READ MORE

  5. 3. Dysfunction in the nigrostriatal system : effects of L-DOPA and GDNF

    Author : Nina Nevalainen; Ingrid Strömberg; Nancy Zahniser; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; L-DOPA; dyskinesia; GDNF; dopamine; glutamate; serotonin; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Abstract : Parkinson’s disease is a common neurodegenerative disorder caused by nigrostriatal dopamine loss, with motor deficiencies as the primary outcome. To increase the striatal dopamine content, patients are treated with 3,4-dihydroxyphenyl-l-alanine (l-DOPA). READ MORE

  6. 4. Involvement of non-dopaminergic systems in L-DOPA-induced dyskinsia

    Author : Daniella Rylander; Basala gangliernas patofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; Dyskinesia; L-DOPA; 6-OHDA rat model; MPTP monkey model; glutamate; serotonin; DA.; 5-HT;

    Abstract : Parkinson's disease and L-DOPA-induced dyskinesia (LID) does not merely involve the dopamine (DA) system but also include non-dopaminergic systems such as glutamate and serotonin (5-HT). An aberrant glutamate transmission at the corticostriatal synapse, has been linked to LID. READ MORE

  7. 5. To metal, or not to metal : Diverse mechanisms of O2-activation and radical storage in the ferritin superfamily

    Author : Vivek Srinivas; Martin Högbom; Brian Hoffman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metalloprotein; di-metal; Oxygen activation; Substrate oxidation; Ribonucleotide reductase; Radical; DOPA; ADE-DOT; X-Ray free-electron laser; soluble Methane monooxygenase; Biochemistry; biokemi;

    Abstract : Proteins in the Ferritin-like superfamily are characterized by a four alpha-helical structural motif. These proteins are distributed across all three kingdoms of life and perform a wide range of functions. READ MORE