Search for dissertations about: "Dopamine"

Showing result 11 - 15 of 466 swedish dissertations containing the word Dopamine.

2. 11. Imaging serotonin and dopamine transporters in social anxiety disorder : Characterization, treatment and expectancy effects

   Author : Olof Hjorth; Tomas Furmark; Andreas Frick; Eduard Maron; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PET; serotonin; dopamine; placebo; SSRI; CBT; MRI; Psychology; Psykologi; Psychiatry; Psykiatri; Radiology; Radiologi;

   Abstract : The monoamines serotonin and dopamine are likely to be involved in the pathophysiology of social anxiety and other affective disorders, but their respective contributions and putative interactions in the causes and cures of these disorders are still not well understood. It is also largely unknown if and how expectations of treatment success affect brain neurochemistry and neural activations, and if expectations interact with antidepressants like selective serotonin reuptake inhibitors (SSRIs). READ MORE

4. 12. Dopamine and the regulation of movements - significance of nigral and striatal dopamine release in normal, hemiparkinsonian and dyskinetic rats

   Author : Daniel Andersson; Göteborgs universitet; []
   Keywords : dopamine; substantia nigra; striatum; L-DOPA; dyskinesias; serotonin;

   Abstract : Introduction: The nigrostriatal dopamine (DA) containing neurones are a pivotal component in the basal ganglia, a network that regulates movement. Degeneration of these neurones causes the cardinal symptoms of Parkinson’s disease (PD). READ MORE

5. 13. Pharmacological and genetic manipulation of adipose cell differentiation and metabolism

   Author : Milica Vranic; Maria J. Pereira; Jan Eriksson; Niklas Mejhert; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; adipocyte; type 2 diabetes; CRISP Cas9; FKBP51; CDKN2C; second-generation antipsychotics; glucocorticoids; dopamine; dopamine receptor;

   Abstract : Adipose tissue dysfunction has a pivotal role in the development of obesity and related metabolic complications, such as insulin resistance, cardiovascular disease, and diabetes. The overall aim was to study the consequences of adipose exposure to pharmacological agents, as well as dysregulations in the expression of genes, potentially involved in adipose tissue dysfunction and related metabolic impairments. READ MORE

6. 14. Striatal pathways in dyskinesia and dystonia

   Author : Laura Andreoli; Basala gangliernas patofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatum; Dystonia; L-DOPA-induced dyskinesia; DREADD; Mouse model; Dopamine; dopamine receptor;

   Abstract : Purposeful and well-coordinated movements depend on the control exerted by dopamine (DA) on the basal ganglia (BG) network. Accordingly, dysfunctions or lesions of the dopaminergic system in the BG can result in an overall poverty and slowness of movement, cardinal features of Parkinson´s disease (PD), or in dyskinesias, exaggerated and involuntary movements resulting from L-DOPA pharmacotherapy. READ MORE

7. 15. The architecture of the aging brain : functional reorganization, structural changes, and the role of dopamine receptors

   Author : Robin Pedersen; Alireza Salami; Anna Rieckmann; Anders Wåhlin; Lars Nyberg; Roser Sala-Llonch; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain architecture; functional connectivity; dopamine; aging; cognition; memory; functional magnetic resonance imaging; positron emission tomography; graph theory; Laplacian eigenmapping; gradient;

   Abstract : Aging is associated with reorganization of functional brain architecture, potentially leading tocognitive decline in older age. However, the mechanisms responsible for alterations in functionalbrain architecture remain poorly understood. READ MORE