Search for dissertations about: "Dosing algorithm"
Showing result 1 - 5 of 9 swedish dissertations containing the words Dosing algorithm.
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1. Automating levodopa dosing schedules for Parkinson’s disease
Abstract : Parkinson’s disease (PD) is the second most common neurodegenerative disease. Levodopa is mainly used to manage the motor symptoms of PD. However, disease progression and long-term use of levodopa cause reduced medication efficacy and side effects. When that happens, precise individualized dosing schedules are required. READ MORE
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2. On the Prediction of Warfarin Dose
Abstract : Warfarin is one of the most widely used anticoagulants in the world. Treatment is complicated by a large inter-individual variation in the dose needed to reach adequate levels of anticoagulation i.e. INR 2. READ MORE
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3. Optimizing levodopa dosing routines for Parkinson’s disease
Abstract : This thesis in the field of microdata analysis aims to introduce dose optimizing algorithms for the pharmacological management of Parkinson’s disease (PD). PD is a neurodegenerative disease that mostly affects the motor functions of the patients and it is characterized as a movement disorder. READ MORE
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4. Garnishing the smorgasbord of pharmacometric methods
Abstract : The smorgasbord of methods that we use within the field of pharmacometrics has developed steadily over several decades and is now a well-laid-out buffet. This thesis adds some garnish to the table in the form of small improvements to the handling of certain problems. READ MORE
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5. Coagulation during and after cardiopulmonary bypass with focus on heparin, protamine, aprotinin and platelet function
Abstract : Background: Heparin and protamine dosing for anticoagulation during cardiopulmonary bypass (CPB) and its reversal after CPB, respectively, is usually given according to body weight. Excess protamine may impair coagulation. The HeProCalc algorithm calculates heparin and protamine doses during the procedure. READ MORE