Search for dissertations about: "Down syndrome"
Showing result 16 - 20 of 101 swedish dissertations containing the words Down syndrome.
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16. Optimizing Chemotherapy in Childhood Acute Myeloid Leukemia
Abstract : Despite major advances in our understanding of the biology of childhood acute myeloid leukemia (AML) and the development of new cytotoxic drugs, the prognosis of long-term survival is still only 60-65 %.In the present research, we studied the pharmacokinetics of drugs used in the induction therapy of childhood AML and performed in vitro drug sensitivity testing of leukemic cells from children with AML. READ MORE
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17. Molecular investigations on chromosome 21 in relation to Down syndrome and familial congenital hypothyroidism
Abstract : Chromosomal abnormalities as well as mutations in single genes are genetic changes that can cause syndromes or inherited diseases. Down syndrome (DS), usually a consequence of trisomy 21, is a gene dosage disorder caused by an extra copy of genes on chromosome 21, but the mechanisms whereby specific genes contribute to the clinical features of DS are not known. READ MORE
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18. Palatal plate therapy in children with Down syndrome : a longitudinal study of effects on oral motor function
Abstract : The aim of this thesis was to investigate the effect of palatal plate therapy on the oral motor function children with Down syndrome (DS) during 4 years by comparing the baseline values of the treatment group with those of a control group (CG). The effects of palatal plate therapy on speech production errors and communicative preference after 4 years of treatment were also studied and articulation was analyzed. READ MORE
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19. The post-polio syndrome : studies of immunology and immunomodulatory intervention
Abstract : Late effects in patients with prior poliomyelitis were first reported in the nineteenth century and have been referred to as the post-polio syndrome (PPS). PPS is characterized by new muscular deterioration, fatigue and pain after a stable period of at least 15 years. READ MORE
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20. Post-polio syndrome : analysis of inflammation and immune modulation
Abstract : Poliomyelitis is a viral infection, which affects the anterior horn cells of the spinal cord leaving patients with different levels and distribution of muscle weakness and loss of, or decreased, function. This situation has previously been regarded as a stable condition. READ MORE