Search for dissertations about: "Dual Specific Antibodies"

Showing result 6 - 10 of 18 swedish dissertations containing the words Dual Specific Antibodies.

  2. 6. Characterisation of epitope-specific B cells and the role of IgG Fc sialylation in murine arthritis models

    Author : Alexander Krämer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autoimmune diseases are a major burden for society and economy. One of the most common autoimmune diseases is rheumatoid arthritis (RA) characterized by joint inflammation, swelling and pain. If left untreated, it ultimately leads to disability. READ MORE

  4. 7. Factors affecting body weight development and eating behaviour in patients on continuous ambulatory peritoneal dialysis treatment

    Author : Anders Fernström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : CAPD; computed tomography; dual energy x-ray absorptiometry; electrogastrography; energy intake; ESRD; gastric emptying; HD; intraabdominal fat; protein-energy malnutrition; taste acuity; taste buds;

    Abstract : Continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD) have different metabolic effects in dialysis patients, since absorption of intraperitoneal glucose implies an additional energy source in CAPD patients. In spite of this, protein-energy malnutrition is known to occur frequently, both in patients on hemodialysis and in patients on CAPD, and an association with increased morbidity and mortality is well established. READ MORE

  5. 8. Structural and Functional Studies on Posttranslational Modifications of Collagen type II in Rheumatoid Arthritis

    Author : Hüseyin Uysal; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The molecular mechanisms behind the development and progression of rheumatoid arthritis are not known in fine details. Both humoral and cellular responses against collagen type II in joint cartilage seems to be important for the disease development. READ MORE

  6. 9. Proximity Extension Assay : a universal tool for proteomics in precision medicine

    Author : Phathutshedzo M. Muthelo; Ulf Landegren; Jochen Schwenk; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proximity Extension Assay; Precision medicine; Assay development; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Precision medicine aims to utilise biomarkers to ensure the right treatment is given to the right patient at the right time. In pursuit of this goal, sensitive protein detection is essential to improve opportunities for discovery, verification, validation and development of valuable protein biomarkers. READ MORE

  7. 10. Interaction engineered three-helix bundle domains for protein recovery and detection

    Author : Tove Alm; Sophia Hober; Rainer Hahn; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ABD; Zbasic; albumin; protein engineering; phage display; staphylococcal display; inclusion bodies; refolding; proteomics; orthogonal affinity purification; Bioengineering; Bioteknik; Immunology engineering; Immunteknik;

    Abstract : HTML clipboard The great advances in DNA technology, e.g. sequencing and recombinant DNA techniques, have given us the genetic information and the tools needed to effectively produce recombinant proteins. Recombinant proteins are valuable means in biotechnological applications and are also emerging as alternatives in therapeutic applications. READ MORE