Search for dissertations about: "Dunning rat model of prostate cancer"

Found 3 swedish dissertations containing the words Dunning rat model of prostate cancer.

  2. 1. Extratumoral effects of highly aggressive prostate cancer

    Author : Kerstin Strömvall; Anders Bergh; Sofia Halin Bergström; Göran Landberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; tumor instructed normal tissue; TINT; non-malignant prostate tissue; lymph nodes; lymph node metastasis; pre-metastatic niche; tumor microenvironment; tumor macroenvironment; tumor immunoediting; Dunning rat model of prostate cancer;

    Abstract : Prostate cancer (PC) is the most common cancer in Sweden. Most patients have slow growing tumors that will not cause them any harm within their lifetime, but some have aggressive tumors and will die from their disease. READ MORE

  4. 2. Prostate cancer and bone cell interactions : implications for metastatic growth and therapy

    Author : Annika Nordstrand; Pernilla Wikström; Anders Widmark; Jonas Nilsson; Päivi Östling; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Oncology;

    Abstract : The skeleton is the most common site of prostate cancer bone metastasis, and at present, there are no curable treatments for these patients. To further understand what stimulates tumor cell growth in the bone microenvironment and to find suitable therapies, reliable model systems are needed. READ MORE

  5. 3. Smad7 in TGF-β Signalling

    Author : Greger Brodin; Stefan Karlsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; TGF-β; Smad7; Prostate; Transcription; Gene targeting; Onkologi; Oncology; Onkologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Members of the transforming growth factor-β (TGF-β) superfamily of growth and differentiation factors regulate a vast array of biological functions in the adult, and are of great importance in governing cell fate determination and patterning in the developing embryo. The TGF-β signal is propagated intracellularly by Smad proteins resulting in transcriptional responses. READ MORE