Search for dissertations about: "E-cadherin"

Showing result 21 - 25 of 59 swedish dissertations containing the word E-cadherin.

  2. 21. Feeling the force : role of AmotL2 in normal development and cancer

    Author : Aravindh Subramani; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cells that fabricate the body, dwell in a very heterogeneous environment. Self-organization of individual cells into complex tissues and organs at the time of growth and revival is brought about by the combinatory action of biomechanical and biochemical signaling processes. READ MORE

  4. 22. Expression and regulation of CCL25 and its role in T cell localization to and function within the small intestine

    Author : Anna Ericsson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosa; epithelium; intestine; transplantation; serology; Immunologi; Immunology; integrin; serologi; Chemokine;

    Abstract : Earlier studies have demonstrated an important role for the chemokine CCL25, and its receptor CCR9, in the generation of the small intestinal lymphocyte compartment. The work in this thesis was aimed at determining how CCL25 is regulated within the small intestinal mucosa, and what potential role it plays in T cell localization to and function within this site. READ MORE

  5. 23. Gastroesophageal reflux disease - complications and prognostic aspects

    Author : Dan Falkenback; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroesophageal reflux disease; Barrett s esophagus; natural course; GERD; Adenocarcinoma; prognosis; biomarkers;

    Abstract : This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. READ MORE

  6. 24. Analysis of signaling pathway activity in single cells using the in situ Proximity Ligation Assay

    Author : Linda Arngården; Ola Söderberg; Niclas Karlsson; Uppsala universitet; []
    Keywords : cell signaling; Wnt; Hippo; TGFB; Molekylär medicin; Molecular Medicine;

    Abstract : A cell that senses signals from its environment uses proteins for signal transduction via post translational modifications (PTMs) and protein- protein interactions (PPIs) from cell membrane into the nucleus where genes controlling cell proliferation, differentiation and apoptosis can be turned on or off, i.e. READ MORE

  7. 25. The role of angiopoietin-like 4 in inflammation

    Author : Terri Phua; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Inflammation is a homeostatically fundamental feature of the host defence surveillance system made up of an army of sentinel cells that guard against foreign intrusion. At the onslaught of an attack, primary immune responders (macrophages and neutrophils) secrete a plethora of cytokines and chemokines that attract secondary responders (T and B cells) to the site of inflammation, to eliminate the intrusion and encourage tissue healing. READ MORE