Search for dissertations about: "E-cadherin"

Showing result 6 - 10 of 59 swedish dissertations containing the word E-cadherin.

  1. 6. Transcriptional and Epigenetic Regulation of Epithelial-Mesenchymal Transition

    Author : E-Jean Tan; Aristidis Moustakas; Carl-Henrik Heldin; Geert Berx; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGFβ; EMT; HMGA2; Snail; Twist; E-cadherin; epigenetics; invasion; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : The transforming growth factor beta (TGFβ) is a cytokine that regulates a plethora of cellular processes such as cell proliferation, differentiation, migration and apoptosis. TGFβ signals via serine/threonine kinase receptors and activates the Smads to regulate gene expression. READ MORE

  2. 7. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer

    Author : Catharina Hagerling; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Wnt5a; E-cadherin; B-catenin; migration; invasion; turnor associated macrophages; CD163; CD68; turnor stroma;

    Abstract : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. READ MORE

  3. 8. Interactions between the stroma and thyroid epithelial cells of normal and malignant origin

    Author : Thérèse Dahlman; Uppsala universitet; []
    Keywords : Medical sciences; Thyroid gland; carcinoma; collagen type I; EGF; TGF-b1; interaction; integrins; E-cadherin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Endocrine and locally produced factors as well as interactions between epithelial cells and the stroma important in the control of growth and function of the thyroid gland. In this study, the effects of, and mechanism(s) for, such cross-talk under some normal and pathological conditions were investigated. READ MORE

  4. 9. Effects of c-erbB2 signaling on morphogenesis and cell adhesion in mammary epithelial cells

    Author : Lachmi E Jenndahl; Göteborgs universitet; []
    Keywords : e-erbB2; integrin alpha2beta1; integrin regulation; ILK; PKB; Rho; epithelial-mesenchymal transition EMT ; E-cadherin; Anchorage independent growth AIG ;

    Abstract : .... READ MORE

  5. 10. A study of the cell adhesions molecules, E-cadherin and C-CAM, and the intermediate filaments, nestin, in craniofacial and tooth development

    Author : Catharina Terling; Karolinska Institutet; Karolinska Institutet; []
    Keywords : cell adhesion molecules; epithelial fusion; C-CAM; E-cadherin; junctional epithelium; nestin; odontogenesis; palate;

    Abstract : Cell adhesion molecules (CAMs) are involved in cell migration, morphogenesis, and cell differentiation within the embryo, and later in the maintenance of the multicellular organism. The aim of the present investigation was to analyze and compare the distribution of the CAMs, E-cadherin and C-CAM, during odontogenesis and palate formation, and furthermore, to analyze the expression of the intermediate filament (IF), nestin, in odontogenesis. READ MORE