Search for dissertations about: "E2"

Showing result 1 - 5 of 221 swedish dissertations containing the word E2.

  2. 1. Studies of prostaglandin E2 formationin human monocytes

    Author : Sofia Karlsson; Jonny Wijkander; Christina Gustafson-Svärd; Karlstads universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostaglandin E2; arachidonic acid; phospholipase A2; cyclooxygenase; prostaglandin E synthase; human monocytes; Medical cell biology; Medicinsk cellbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Prostaglandin (PG) E2 is an eicosanoid derived from the polyunsaturated twenty carbon fatty acid arachidonic acid (AA). PGE2 has physiological as well as pathophysiological functions and is known to be a key mediator of inflammatory responses. READ MORE

  4. 2. Prostaglandin E2 in Brain-mediated Illness Responses

    Author : Louise Elander; Anders Blomqvist; Marianne Schultzberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostaglandin e2; PGE2; cox-1; cox-2; mPGES-1; fever; anorexia; food intake; HPA-axis; EP-receptor; LPS; IL-1; IL-6; MEDICINE; MEDICIN; Neurobiology; Neurobiologi;

    Abstract : We are unceasingly exposed to potentially harmful microorganisms. The battle against threatening infectious agents includes activation of both the innate and of the adaptive immune systems. READ MORE

  5. 3. Concerted and stepwise solvolytic elimination and substitution reactions : evidence for solvent-promoted E2 reaction

    Author : Qingshui Meng; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  6. 4. Prostaglandin E2 in immune-to-brain signaling

    Author : David Engblom; Tamas Bartfai; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Upon immune-challenge, signaling from the immune system to the brain triggers an array of central nervous responses that include fever, anorexia, hyperalgesia and activation of the hypothalamus-pituitary adrenal axis. These symptoms are dependent on cytokines produced at the site of inflammation. READ MORE

  7. 5. Regulation of prostaglandin E2 synthesis in human gingival fibroblasts

    Author : Tülay Yucel-Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : prostaglandin E2; cyclooxygenase; phospholipase A2 interleukin-1; tumor necrosis factor [alpha]; epidermal growth factor; protein kinase C; tyrosine kinases; human gingival fibroblasts;

    Abstract : Prostaglandins, especially, prostaglandin E2 (PGE2) play an important role in inflammatory diseases such as rheumatoid arthritis and periodontitis. The aim of the present thesis was to study the production and the regulation of PGE2 with special reference to the key enzymes phospholipase A2 (PLA2) and cyclooxygenase (COX) at the rnRNA level in human gingival fibroblasts. READ MORE