Search for dissertations about: "E4-ORF6 proteins"

Found 2 swedish dissertations containing the words E4-ORF6 proteins.

  2. 1. Viral Strategies to Regulate Transcription and Pre-mRNA Splicing

    Author : Shaoan Fan; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Adenovirus E1B-55kDa; E4-ORF4; E4-ORF6 proteins; L1 mRNA; Polyoma virus small T antigen; regulation; transcription; splicing; PP2A; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : A typical DNA virus encodes for a few key regulatory proteins that modify the host cell biosynthetic machinery to achieve a selective viral gene statement. One such example is illustrated by the adenovirus E4-ORF4 protein, which form an enzymatically active complex with the serine and threonine-specific protein phosphatase 2A (PP2A). READ MORE

  4. 2. Function of adenovirus early region 4 proteins in RNA processing and cellular transformation

    Author : Karin Öhman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adenovirus; Adenovirus early region 4; pre-mRNA splicing; alternative splicing; cellulartransformation.;

    Abstract : For almost 30 years, adenovirus has been used as a model system for mechanistic studies of eucaryote gene expression. In this thesis, we have concentrated our efforts to investigate the function of adenovirus early region 4 (E4) gene products in cellular transformation and the post-transcriptional regulation of gene expression. READ MORE