Search for dissertations about: "E6"

Showing result 11 - 15 of 45 swedish dissertations containing the word E6.

  2. 11. Modulation of the deubiquitnating system during lymphoid cell activation and viral infection

    Author : Ulrika Rolén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The family of ubiquitin-specific proteases (USPs) removes ubiquitin from its conjugates and regulates the production and recycling of ubiquitin. USPs are thereby critically involved in the control of important functions such as cell growth, differentiation and apoptosis. Increasing evidence implicates USPs deregulation in malignant transformation. READ MORE

  4. 12. Pharmacological targeting of p53 pathway alterations in tumors

    Author : Ying Zhao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The p53 tumor suppressor plays an important role in cell fate decisions upon diverse stress conditions. In response to stress, p53 functions as a transcription factor, activating transcription of a variety of its target genes responsible for several cellular responses, most importantly cell cycle arrest and apoptosis. READ MORE

  5. 13. On the Clebsch-Gordan problem for quiver representations

    Author : Martin Herschend; Ernst Dieterich; Alex Martsinkovsky; Karin Erdmann; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Algebra and geometry; quiver; quiver representation; tensor product; Clebsch-Gordan problem; representation ring; bialgebra; Galois covering; Algebra och geometri;

    Abstract : On the category of representations of a given quiver we define a tensor product point-wise and arrow-wise. The corresponding Clebsch-Gordan problem of how the tensor product of indecomposable representations decomposes into a direct sum of indecomposable representations is the topic of this thesis. READ MORE

  6. 14. Occurrence of human papillomaviruses (HPV) types in HPV related cancer and in the genital and oral tracts of young adults

    Author : Juan Du; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human papillomavirus (HPV) is associated to cancer of the uterine cervix, the third most common cancer among women, but also to head and neck squamous cell carcinoma (HNSCC), the sixth most common type of cancer in the world. HPV occurs in most cervical cancer (CC). READ MORE

  7. 15. Molecular mechanisms in cervical carcinogenesis : Studies of clonality, somatic genetic alterations and human papillomavirus variants in cervical pre-invasive and invasive cancer

    Author : Zhongmin Guo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical cancer; CIN; clonality; X-chromosome inactivation; LOH; HPV; chromosome 3p; chromosome 6; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Cervical cancer derives from a series of pre-invasive cervical neoplastic lesions termed CIN I-III (Cervical Intraepithelial Neoplasia) via typical multiple-step processes. In contrast to premalignant disorders in other organs, different degrees of CIN possess a distinct biological behaviour where a proportion spontaneously regress or persist, whereas some progress to invasive cancer. READ MORE