Search for dissertations about: "EBNA1"

Showing result 1 - 5 of 27 swedish dissertations containing the word EBNA1.

  1. 1. Regulation of the Epstein-Barr virus C promoter by the OriP-EBNA1 complex

    Author : Cecilia Boreström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Epstein-Barr virus; EBNA1; NF-Y; Sp1; Oct-2; Bright; E2F1; transcriptional regulation; Cp; oriP;

    Abstract : Epstein-Barr Virus (EBV) is an exclusively human, lymphotropic herpes virus that infects more than 90% of the population worldwide. Primary infection usually occurs during the early years of life and does not result in any recognized disease. READ MORE

  2. 2. Transcriptional regulation of the Epstein-Barr virus nuclear antigen 1 gene in latent and lytic stages of infection

    Author : Henrik Zetterberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ; Epstein-Barr virus; EBNA1; Burkitt s lymphoma; nasopharyngeal carcinoma; B-lymphocyte; transformation; transcriptional regulation;

    Abstract : Epstein-Barr virus (EBV) is a lymphotropic herpesvirus that infects more than 90% of humans worldwide. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disorder, and is also associated with a variety of malignancies including Burkitt's lymphoma (BL), Hodgkin's disease (HD), nasopharyngeal carcinoma (NPC), and lymphoproliferative disorders in immunocompromised individuals. READ MORE

  3. 3. Characterization of non-coding mRNA in Epstein-Barr virus

    Author : Åsa Isaksson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Epstein-Barr virus; EBNA1; IRES; PTLD; alternative splice; nucleotide substitution; protein interactions;

    Abstract : Epstein-Barr virus (EBV) is a human gammaherpesvirus that infects lymphoid and epithelial cells. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disease, and it is additionally associated with various malignancies including Burkitt?s lymphoma, Hodgkin?s disease and lymphoproliferative syndromes in immunocompromised individuals. READ MORE

  4. 4. The Epstein-Barr nuclear antigens 1 & 5; Study of virus-host cellular protein interactions

    Author : Alma Forsman; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; EBNA1; EBNA5; EBNA-LP; cellular network; virus-host protein interactions;

    Abstract : The Epstein-Barr virus (EBV) is the causative agent or cofactor in the aetiology of several human malignancies such as Burkitt’s lymphoma, Hodgkin’s disease, nasopharyngeal carcinoma (NPC) and lymphoproliferative disorder in immunocompromised patients. EBV is a lymphotropic γ-herpes virus infecting more than 90 percent of the population worldwide. READ MORE

  5. 5. EBV gene variation and epigenetic alterations in asian nasopharyngeal carcinoma and potential clinical applications

    Author : Do Nguyen-Van; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; EBV; EBNA1; LMP1; LMP2A; FR; Q locus; genetic variation; antisense oligonucleotide; CDH13; DNA methylation; epigenetics; nasopharyngeal carcinoma;

    Abstract : The incidence of nasopharyngeal carcinoma (NPC), an epithelial tumor, varies remarkably in different geographic regions and human populations. The Epstein-Barr virus (EBV), other environmental factors and genetic susceptibility are all considered to be involved in the etiology of this form of cancer and the EBV has been extensively studied in this context. READ MORE