Search for dissertations about: "EDSS"
Showing result 1 - 5 of 14 swedish dissertations containing the word EDSS.
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1. Longitudinal Models for Quantifying Disease and Therapeutic Response in Multiple Sclerosis
Abstract : Treatment of patients with multiple sclerosis (MS) and development of new therapies have been challenging due to the disease complexity and slow progression, and the limited sensitivity of available clinical outcomes. Modeling and simulation has become an increasingly important component in drug development and in post-marketing optimization of use of medication. READ MORE
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2. Brain parenchymal fraction in healthy individuals and in clinical follow-up of multiple sclerosis
Abstract : Background Multiple sclerosis (MS) is an autoimmune disease characterised by inflammatory damage to the central nervous system (CNS). Accumulated CNS injury can be quantified as brain atrophy, definable as a reduction in brain parenchymal fraction (BPF). BPF correlate with disability in MS and is used routinely as an endpoint in clinical trials. READ MORE
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3. Work ability in multiple sclerosis : the impact of immunomodulating treatments and adjusted working conditions
Abstract : Background Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease affecting the central nervous system (CNS) and is considered to be of autoimmune origin. The prevalence in Sweden is estimated to be about 1 in 500. READ MORE
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4. Cognitive function and neurophysiological correlates in relapsing-remitting multiple sclerosis
Abstract : Impaired cognitive function is a frequent consequence of multiple sclerosis (MS). It negatively affects vocational status, treatment adherence, physical independence, competence in activities of daily life, rehabilitation potential, driving safety and quality of life. READ MORE
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5. Environmental Monitoring of Refuse Dump Leachate Toxicity in Fish
Abstract : The global economy is driven by the consumption of goods and materials. Used products are often deposited on refuse dumps, making them potential point sources for all man-made chemicals. Water soaking through landfill waste results in a wastewater termed leachate. READ MORE