Search for dissertations about: "EGF"

Showing result 1 - 5 of 126 swedish dissertations containing the word EGF.

  1. 1. Tumour Targeting Using Radiolabelled EGF Conjugates Preclinical Studies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Åsa Liljegren Sundberg; Jörgen Carlsson; Lars Gedda; Vladimir Tolmachev; Erik Blomquist; Gregory P. Adams; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; targeting; tumour; EGF; radionuclide; gefitinib; Iressa; ZD1839; glioma; therapy; diagnostics; Strålningsvetenskap; MEDICINE Physiology and pharmacology Radiological research Radiation biology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Strålningsbiologi;

    Abstract : Tumour targeted radiotherapy is an appealing approach for treatment of disseminated tumour cells. A targeting agent that specifically binds to a structure on tumour cells is then used to transport therapeutically relevant radionuclides. The epidermal growth factor receptor, EGFR, is overexpressed on tumour cells in several malignancies, e.g. READ MORE

  2. 2. Targeting to EGF receptors : effects of native or radiolabelled EGF on cultured glioma cells and its distribution in vivo

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jacek Capala; [1991]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  3. 3. Targeting to EGF receptors : preparation of EGF-dextran conjugates and analysis of their metabolism in vitro and in vivo

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Annelie Lindström; [1993]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  4. 4. Targeting to EGF receptors : Preparation and experimental analysis of end-end coupled mEGF-dextran conjugates

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Qinghai Zhao; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Abstract : Targeted tumor therapy is to deliver cytotoxic agents selectively to tumor cells. By such delivery, normal tissues receive minimal damage while a therapeutical effect is achieved in tumor. A targetingsystem can be constructed by conjugating a tumor-seeking molecule and toxic agents via a carrier. READ MORE

  5. 5. Growth factor regulation of the urokinase plasminogen activator (uPA) system in human endometrium, and the significance of uPA receptor activation in endometrial angiogenesis

    University dissertation from Institutionen för Obstetrik och gynekologi, Universitetssjukhuset, 22185 Lund

    Author : Tove Sandberg; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; endothelial cell migration; angiogenesis; uPA:PAI-1 complex; uPAR; TGF-beta; PAI-1; EGF; uPA; Growth factor; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : The purpose of this thesis was to examine the role of growth factors and the urokinase plasminogen activator (uPA) system in human endometrial angiogenesis. Growth factors as well as progesterone increased expression of the main inhibitor of uPA (PAI-1) in primary cultures of endometrial stromal cells. READ MORE