Search for dissertations about: "ELECTROSPRAY-IONIZATION"
Showing result 1 - 5 of 82 swedish dissertations containing the word ELECTROSPRAY-IONIZATION.
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1. Mass Spectrometry with Electrospray Ionization from an Adjustable Gap
Abstract : In this thesis the fabrication and analytical evaluation of two new electrospray emitters utilized for mass spectrometry analysis is presented. The emitters are based on a new concept, where the spray orifice can be varied in size. The thesis is based on two papers. All present-day nanoelectrospray emitters have fixed dimensions. READ MORE
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2. Electrospray Ionization Mass Spectrometry for Determination of Noncovalent Interactions in Drug Discovery
Abstract : Noncovalent interactions are involved in many biological processes in which biomolecules bind specifically and reversibly to a partner. Often, proteins do not have a biological activity without the presence of a partner, a ligand. READ MORE
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3. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides
Abstract : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. READ MORE
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4. Applications of nanospray desorption electrospray ionization mass spectrometry : In situ lipid and metabolite analysis from cells to tissue
Abstract : Ambient mass spectrometry (MS) has proved to be an important addition to the bioanalytical toolbox. These methods perform analyte sampling and ionization under atmospheric pressure, and require very little sample preparation other than the sampling process in front of the machine. READ MORE
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5. Electrifying the Molecules of Life : Peptide and Protein Analysis by Capillary Electrophoresis Coupled to Electrospray Ionization Mass Spectrometry
Abstract : This thesis describes the current status and novel aspects of the analysis of the molecules of life, i.e. peptides and proteins, using capillary electrophoresis (CE) coupled to mass spectrometry (MS) via (sheathless) electrospray ionization (ESI). Early reports of sheathless CE-ESI-MS were plagued by limited lifetimes of the electrospray emitter. READ MORE