Search for dissertations about: "EP2"
Showing result 1 - 5 of 8 swedish dissertations containing the word EP2.
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1. Involvement of vasopressin and oxytocin in the regulation of human uterine activity
Abstract : Vasopressin and oxytocin seem to have pivotal roles in the pathophysiology of primary dysmenorrhoea and preterm labour. Prostaglandins are also involved in the regulation of uterine activity with different receptors mediating both stimulation and relaxation. READ MORE
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2. Prostaglandin E2 as mediator and modulator of airway smooth muscle responses
Abstract : Prostaglandin E2 (PGE2) is a lipid mediator produced by virtually every cell of the human body. Because common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit its biosynthesis, PGE2 is usually considered to be a ‘pro-inflammatory’ mediator. The role of PGE2 in the lung and airways has however always been unclear. READ MORE
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3. Effects of Inflammatory Mediators on Pulmonary Airways
Abstract : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. READ MORE
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4. New insights on type 2 immunity key drivers : mast cells and group 2 innate lymphoid cells
Abstract : Type 2 immune responses are characterized by the production of cytokines IL-4, IL-5 and IL-13. They are known to have crucial physiological and pathophysiological functions in the body. Data from recent studies indicate their importance in the containment and clearance of helminth infections. READ MORE
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5. Tumor progression in the ovary and colon. The interaction of Wnt-signaling, transcription and formation of prostaglandins
Abstract : Alterations in cell-cell adhesion, intracellular signaling and transcriptional regulation are common events during transformation of cells to the malignant phenotype. Different cellular defense mechanisms, e.g. inflammatory responses, mediated by prostaglandins, have also been associated with tumor development. READ MORE