Search for dissertations about: "EPO receptor EPOR"
Found 2 swedish dissertations containing the words EPO receptor EPOR.
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1. Translational Aspects of Erythropoietin Receptor and Hypoxia-Inducible Factors in Breast Cancer
Abstract : The main function of erythropoietin (EPO) is in hematopoiesis where EPO stimulates increased proliferation, survival and differentiation of erythrocytic precursors in response to hypoxia. The EPO effect is mediated via binding to the EPO receptor (EPOR), which induces activation of different intracellular signaling pathways. READ MORE
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2. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer
Abstract : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. READ MORE