Search for dissertations about: "ERβ"

Showing result 1 - 5 of 45 swedish dissertations containing the word ERβ.

  2. 1. Life Style, Molecular Pathology, and Breast Cancer Risk

    Author : Signe Borgquist; Malmö Handkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone receptors; Breast cancer; tissue microarray; histopathology; ERβ; tumour proliferation; cyclin D1; p27; HMG-CoA reductas; life style factors; diet; hormone replacement therapy; obesity; endocrine therapy;

    Abstract : The breast cancer diagnosis covers a wide range of tumours with different geno- and phenotypic characteristics. The diversity among studies on life-style factors and their impact on breast cancer risk might be clarified by recognizing breast cancer as a heterogeneous disease. READ MORE

  4. 2. Roles of ERα and ERβ in Normal and Disrupted Sex Differentiation in Japanese Quail

    Author : Anna Mattsson; Björn Brunström; Krister Halldin; Lena Sahlin; Uppsala universitet; []
    Keywords : Toxicology; sex differentiation; estrogen receptor; sexual behavior; endocrine disruption; Japanese quail; Toxikologi;

    Abstract : Exposure to xenoestrogens during development has been shown to impair sexual differentiation in various species. The major aim of this thesis was to elucidate the respective roles of the two estrogen receptors ERα and ERβ in normal and disrupted differentiation of sex organs and copulatory behavior in the Japanese quail (Coturnix japonica). READ MORE

  5. 3. Role and mechanism of estrogen receptor beta in the ovary and colon

    Author : Madeleine Birgersson; Cecilia Williams; Amena Archer; Claudia Kutter; Eduardo Villablanca; David Moore; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinsk teknologi; Medical Technology;

    Abstract : Estrogen regulates a variety of important physiological functions in both males and females, where the regulation of female reproduction and the development of sexual organs are typical examples. The effects of estrogen are predominantly exerted via signaling through the two nuclear receptors estrogen receptor α (ERα) and β (ERβ), or the membrane G protein-coupled estrogen receptor 1 (GPER1). READ MORE

  6. 4. Estrogen receptor β signalling in mammary epithelial and breast cancer cells

    Author : Karolina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Estrogens are key players in the etiology and progression of breast cancer, and mediate their effects through the estrogen receptors (ERα and ERβ). ERα plays important roles in proliferation and progression of breast cancer, whereas a distinct function of ERβ in the initiation and development of breast cancer is not yet clearly established. READ MORE

  7. 5. Exploring the genome-wide impact of estrogen receptor alpha and estrogen receptor beta in breast and colon cancer cells

    Author : Karin Edvardsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Estrogen signaling is involved in the development and progression of breast cancer and is implicated to be protective in colon cancer. Estrogenic actions are conveyed through transcriptional regulation by ligand stimulated estrogen receptors (ERα and ERβ). READ MORE