Search for dissertations about: "ER stress"

Showing result 21 - 25 of 81 swedish dissertations containing the words ER stress.

  2. 21. Carbon exchange in boreal ecosystems: upscaling and the impacts of natural disturbances

    Author : Julia Kelly; BECC: Biodiversity and Ecosystem services in a Changing Climate; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Carbon fluxes; CH4; Climate change; CO2; Drought; Ecosystem respiration; Forest; Peatland; Remote sensing; Temperature; Thermal camera; UAV; Wildfire;

    Abstract : Boreal forests and peatlands are globally significant carbon stores but they are threatened by rising air temperatures and changes in precipitation regimes and the frequency of natural disturbances. Predicting how the boreal biome will respond to climate change depends on being able to accurately model and upscale the greenhouse gas fluxes between these ecosystems and the atmosphere. READ MORE

  4. 22. The role of the ubiquitin-proteasome system in neurodegenerative disorders

    Author : Lisette Gerridina Gezina Catharina Verhoef; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Degradation; green fluorescent protein GFP ; neurodegeneration; polyglutamine; proteasome; UBB 1; ubiquitin;

    Abstract : Neurodegenerative disorders are a heterogeneous group of clinically and pathologically diverse diseases. The diseases are characterised by selective loss of neurons. in specific regions of the brain. The result is disruption of motor, sensory or cognitive systems, leading to severe disability of the patients. READ MORE

  5. 23. Regulation and Function of the Human Leukotriene D4 Receptor CysLT1 in Epithelial Cells and Colon Cancer

    Author : Christian Kamp-Nielsen; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; Inflammation; PKC; Calcium; CysLT1R; GPCR; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : The pro-inflammatory mediators leukotrienes have shown to be important players in the pathogenesis of diseases like asthma and inflammatory bowel disease (IBD). Patients suffering from IBD have been found to have an increased risk of developing colon cancer. READ MORE

  6. 24. Mechanisms for and consequences of cellular lipid accumulation - Role of the Very Low Density Lipoprotein (VLDL) receptor

    Author : Jeanna Perman; Göteborgs universitet; []
    Keywords : very low density lipoprotein receptor; lipid accumulation;

    Abstract : Lipid accumulation in non adipose tissue is associated with various cases of tissue dysfunction and tissue failure. Reduced availability of oxygen is known to cause intracellular lipid accumulation in cardiomyocytes as well as in hearts. READ MORE

  7. 25. Characterisation of the novel endoplasmic reticulum chaperone ERDJ5

    Author : Paula Cunnea; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Endoplasmic reticulum; chaperone; unfolded protein response; protein folding; disease;

    Abstract : Communication between cells depends to a large extent on interactions between secreted proteins and membrane receptors. Therefore their production and release must be strictly regulated. Proteins that are destined for the extracellular space assemble and fold in the endoplasmic reticulum (ER). READ MORE