Search for dissertations about: "ERG gene"

Showing result 1 - 5 of 14 swedish dissertations containing the words ERG gene.

  2. 1. Evaluation of the visual pathway with ERG, mfERG and mfVEP in inherited eye disorders

    Author : Lotta Gränse; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; multifocal ERG; Full-field ERG; multifocal VEP; Bothnia Dystrophy; Retinitis pigmentosa; Dominant optic atrophy; Leber`s hereditary optic neuropathy; Oftalmologi; Ophtalmology;

    Abstract : This thesis will describe the clinical phenotypes, with emphasis on electrophysiology, in patients with different hereditary eye diseases and to further evaluate and modify the mfVEP technique for clinical use. Bothnia Dystrophy is a tapetoretinal disorder with a mutation in the RLBP1 gene. READ MORE

  4. 2. Genetic variation and prostate cancer : population-based association studies in Sweden

    Author : Sara Lindström; Henrik Grönberg; Fredrik Wiklund; John Todd; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; epidemiology; SRD5A2; ERG; progression; genetics; association studies; polymorphism; haplotype; CDH1; AR; CYP17; Oncology; Onkologi;

    Abstract : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. READ MORE

  5. 3. Prognostic markers in pediatric leukemia and mechanisms of KRAS induced leukemogenesis

    Author : Anna Staffas; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prognostic markers; AML; T-ALL; leukemia; FLT3; NPM1; ERG; BAALC; KRAS;

    Abstract : Leukemia results from uncontrolled growth of genetically altered blood cells. Depending on the cell type of origin, the leukemia is defined as T-cell, B-cell, or myeloid and as acute or chronic depending on its characteristics. However, patients with a certain subtype of leukemia (e.g. READ MORE

  6. 4. Assessing the ERG rearrangement for clinincal use in patients with prostrate cancer

    Author : Maria Svensson; Ove Andrén; Swen-Olof Andersson; Fredrik Enlund; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prognosis; biomarkers; ETS genes; ERG rearrangement; fluoroscence in situ hybridization; Medicine; Medicin;

    Abstract : In Sweden, close to 10 000 men are annually diagnosed with prostate cancer (PCa) and approximately 2400 men die of their disease each year. Today there is no reliable marker that can separate patients who will have an aggressive type of disease that requires treatment, from patients who will have a more indolent clinical course and can be left untreated. READ MORE

  7. 5. Clinical expressions of juvenile hereditary retinal degenerations and macular dystrophies: Electrophysiological and genetic studies

    Author : Louise Eksandh; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oftalmologi; Ophtalmology; Rod-monochromacy; Stargardt disease; Juvenile X-linked retinoschisis; Spielmeyer-Vogt disease; Best disease; multifocal-ERG; EOG; full-field ERG; Phenotype; genotype;

    Abstract : Hereditary retinal degenerations are the most frequent reason for severe visual handicap among young people in Scandinavia today. In the six papers included in this thesis the phenotypic expressions, with emphasis on the electrophysiological findings, of five different juvenile hereditary retinal degenerations are described. READ MORE