Search for dissertations about: "ESCRT"
Showing result 1 - 5 of 10 swedish dissertations containing the word ESCRT.
-
1. Characterizing important flavivirus-host interactions : Replication, assembly, restriction factors and vaccine development
Abstract : The genus Flavivirus (family Flaviviridae) consists of important zoonotic viruses that cause morbidity and mortality worldwide. These viruses are enveloped and have a positive-sense single-stranded RNA genome encoding a polyprotein. READ MORE
-
2. Divisive structures : Two billions years of biofilament evolution
Abstract : Our understanding of the functional and regulatory complexity that existed in the eukaryotic progenitor is poor, and investigations have been hindered by our nebulous understanding of where eukaryotes stem from. Recently discovered archaeal lineages with hitherto unseen homology to eukaryotic systems suggest archaea can further our understanding of the eukaryotic cell’s ancestry. READ MORE
-
3. Unique Solutions to Universal Problems : Studies of the Archaeal Cell
Abstract : Archaea is one of the three domains of life and studies of archaeal biology are important for understanding of life in extreme environments, fundamental biogeochemical processes, the origin of life, the eukaryotic cell and their own, unique biology. This thesis presents four studies of the archaeal cell, using the extremophilic Sulfolobus and ocean living Nitrosopumilus as model systems. READ MORE
-
4. The release of histone proteins from cells via extracellular vesicles
Abstract : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. READ MORE
-
5. Adhesion-dependent mechanisms regulating mitosis
Abstract : Integrin-mediated cell adhesion is required for normal cell cycle progression during G1-S transition and for the completion of cytokinesis. Cancer cells have ability to grow anchorage-independently, but the underlying mechanisms and the functional significance for cancer development are unclear. READ MORE