Search for dissertations about: "ESI MS"

Showing result 1 - 5 of 102 swedish dissertations containing the words ESI MS.

  2. 1. Novel Solid Phase Extraction and Mass Spectrometry Approaches to Multicomponent Analyses in Complex Matrices

    Author : Nahid Amini; Gunnar Thorsén; Tuulia Hyötyläinen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Sample preparation; SPE; RAM; GCB µ-trap; GCB disk; High temperature LC; LC MS; ESI; APCI; Matrix effects; LIT-MS; SALDI; Sample screening; Oxidized GCB; Silicon nitride; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : Analysis of compounds present in complex matrices is always a challenge, which can be partly overcome by applying various sample preparation techniques prior to detection. Ideally, the extraction techniques should be as selective as possible, to minimize the concentration of interfering substances. READ MORE

  4. 2. Mass Spectrometry with Electrospray Ionization from an Adjustable Gap

    Author : Patrik Ek; Åsa Emmer; Johan Roeraade; Per M. Claesson; Ulrika Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Electrospray ionization; mass spectrometry; nanoelectrospray; ESI; MS; chip; emitter; gap; liquid bridge; nozzle; peptides; Analytical chemistry; Analytisk kemi;

    Abstract : In this thesis the fabrication and analytical evaluation of two new electrospray emitters utilized for mass spectrometry analysis is presented. The emitters are based on a new concept, where the spray orifice can be varied in size. The thesis is based on two papers. All present-day nanoelectrospray emitters have fixed dimensions. READ MORE

  5. 3. Interfacing HPLC with MALDI- and ESI-MS for Automated High Sensitivity Analysis of Proteins and Peptides

    Author : Tasso Miliotis; Lund Institutionen för kliniska vetenskaper; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; automated; phosphorylation; ZAP-70; peptides; proteins; comprehensive; multidimensional; two-dimensional; piezoelectric; microdispenser; flow-through; ESI-MS MS; Capillary HPLC; MALDI-TOF MS; Analytical chemistry; Analytisk kemi;

    Abstract : The research described in this thesis has an interdisciplinary approach dealing with chemical, biological, and technical issues. One objective was to interface miniaturized liquid chromatography (LC) to mass spectrometry, i.e. MALDI-TOF MS and ESI-MS, in an unattended mode for high sensitivity determination of proteins and peptides. READ MORE

  6. 4. Novel clean-up, concentration and laser desorption/ionization strategies for mass spectrometry

    Author : Mohammadreza Shariatgorji; Leopold Ilag; Juan Astorga-wells; Bernhard Spengler; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; ESI-MS; SALDI-MS; Electrocapture; Sample treatment; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : Despite valuable advantages of mass spectrometry (MS) techniques they still have drawbacks that need to be overcome, notably their sensitivity to various kinds of interfering substances and associated difficulties involved in detecting signals from analytes present in trace quantities. Thus, high quality analytical data could be acquired by improving sample pre-treatment techniques and/or ionization methods to increase ionization yields and/or avoid the generation of unwanted ions. READ MORE

  7. 5. Characterisation of the Substituent Distribution in Starch and Cellulose Derivatives

    Author : Sara Richardson; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Analytisk kemi; Cationic amylopectin; Hydroxypropyl amylopectin; Ethyl hydroxyethyl cellulose; Substituent distribution; Enzymic degradation; HPAEC-PAD; MALDI-TOF-MS; ESI-MS; Kemi; Analytical chemistry;

    Abstract : Starch and cellulose can be chemically modified to produce derivatives with specific properties. Knowledge of correlations between the modification reaction, substituent distribution and properties is important in order to design modification processes so as to produce derivatives with the desired properties. READ MORE