Search for dissertations about: "ESRRA"

Found 1 swedish dissertation containing the word ESRRA.

  1. 1. Transcriptional Regulation of HIF2A/EPAS1 in Neuroblastoma

    University dissertation from Division of Translational Cancer Research

    Author : Arash Hamidian; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIF-2α; enChIP; ESRRA; mTORC2; IGF-II; Hypoxia; Cancer; PI3K; Transcription; Neuroblastoma;

    Abstract : Neuroblastoma is a childhood tumor of the developing sympathetic nervous system (SNS) and is the most commonly diagnosed form of cancer in children before one year of age. Although survival curves have improved for these patients during the past decades, the conventional regimen of neuroblastoma treatment has clearly reached a plateau of efficiency with regard to increasing the survival rates of high-risk children. READ MORE