Search for dissertations about: "Effect on vascular function"
Showing result 1 - 5 of 169 swedish dissertations containing the words Effect on vascular function.
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1. Angiotensin II and vascular disease. Studies in rats and atherosclerosis-prone mice
Abstract : Angiotensin II (Ang II) is of importance for a number of physiological processes but also plays an important pathophysiological role in cardiovascular disease. The aim of this thesis was to evaluate the role of Ang II in hypertension-related atherosclerosis and vascular disease and to investigate possible anti-atherosclerotic effects of the angiotensin II, type 2 (AT2) receptor. READ MORE
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2. On the stimulatory effect of microglial cells on angiogenesis
Abstract : ABSTRACT Angiogenesis, the process by which new vessels sprout from pre-existing vessels, is fundamental to development, tissue growth and repair. The main aim of this thesis was to investigate the role of microglia on angiogenesis. We adapted the rat ex vivo/in vitro aortic ring model to the mouse in a 3-D culture system. READ MORE
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3. Effect of Drugs on Rabbit Retina
Abstract : The adverse effects of drugs in the eye are not easily detected, and the underlying pathogenesis not fully understood. The effects of four different kinds of drugs have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. READ MORE
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4. Role of arginase in vascular function
Abstract : Background: Nitric oxide (NO) is central for the integrity of the cardiovascular system, the maintenance of endothelial function and the protection against ischaemic heart disease. The enzyme arginase is up-regulated during ischaemia-reperfusion and by hypoxia in cell culture and animal models which might be of pathophysiological relevance since it competes with NO synthase for their common substrate arginine. READ MORE
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5. Effects of cigarettes, e-cigarettes and Swedish snus on vascular function
Abstract : Cigarette smoking is considered one of the leading causes of preventable morbidity and premature death worldwide. A large portion of this is attributable to cardiovascular disease such as ischemic heart disease and stroke. READ MORE