Search for dissertations about: "Electrophiles"

Showing result 1 - 5 of 37 swedish dissertations containing the word Electrophiles.

  2. 1. Thermo- and chemosensitive properties of Transient Receptor Potential Ankyrin 1 ion channels

    Author : Lavanya Moparthi; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TRP ion channels; TRPA1; ankyrin repeat domain; thermosensation; chemosensation; cold sensor; electrophiles; non-electrophiles; planar lipid bilayers; patch-clamp; fluorescence spectroscopy; mass spectrometry;

    Abstract : The ability to sense and accommodate to an ever-changing environment is crucial for the survival of living organisms. Transient Receptor Potential (TRP) ion channels comprise a large superfamily of cation conducting membrane proteins that function as molecular sensors in diverse sensory processes including perception of light, taste, smell, sound, touch and temperature. READ MORE

  4. 2. Reactivity of late transition metal complexes towards CO2 and other electrophiles

    Author : Magnus Johnson; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; CO2; carbon dioxide; electrophiles; late transition metal complexes; catalysis; halogen bonding; XB; cyclometallation; pincer; organometallic synthesis;

    Abstract : In times when dwindling energy resources is a major long-term problem for sustaining modern infrastructure and technologies, we need to focus on more enduring solutions. A key contribution to this achievement is catalysis. READ MORE

  5. 3. Characterization of Membrane Proteins: From a gated plant aquaporin to animal ion channel receptors

    Author : Sabeen Survery; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MIPs; AQPs; TRP ion channels; water transport; themo sensor; Electrophiles;

    Abstract : Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. READ MORE

  6. 4. Method for measurement of exposure to electrophiles : Strategy for identification and exposure estimation using N-terminal haemoglobin adducts

    Author : Efstathios Vryonidis; Margareta Törnqvist; Hitesh Motwani; Isabella Karlsson; Marie Pedersen; Gabriele Sabbioni; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Haemoglobin adducts; Electrophilic exposure; LC-MS; Adductomics; Acrylamide; Environmental Sciences; miljövetenskap;

    Abstract : We are exposed to many chemicals in our everyday life. Some of these chemicals could pose risks for our health. To reduce such risks, it is important to know what we are exposed to, how much, and how toxic the chemicals are. READ MORE

  7. 5. Development of an adductomic approach to identify electrophiles in vivo through their hemoglobin adducts

    Author : Henrik Carlsson; Margareta Törnqvist; Gunnar Boysen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Adductomics; Hemoglobin adducts; LC MS MS; Ethyl vinyl ketone; Glyoxal; Methylglyoxal; Acrylic acid; 1-Octen-3-one; Environmental Chemistry; miljökemi;

    Abstract : Humans are exposed to electrophilically reactive compounds, both formed endogenously and from exogenous exposure. Such compounds could react and form stable reaction products, adducts, at nucleophilic sites in proteins and DNA. READ MORE