Search for dissertations about: "Eleni Aklillu"

Found 1 swedish dissertation containing the words Eleni Aklillu.

2. 1. Pharmacogenetics of drug metabolizing enzymes with special emphasis on Ethiopians

   Author : Eleni Aklillu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Drug metabolism; gene duplication; CYP2D6; CYP2C19; CYP2C9; CYP1B1; CYP1A2; genotyping; xanthine oxidase; ultrarapid metabolizers; polymorphism; caffeine; Ets; dietary selection.;

   Abstract : Pharmacogenetics of drug metabolising enzymes has been well studied in Caucasians and Asians, but relatively little in Africans. The aim of this thesis was to investigate the molecular genetics of drug metabolising enzymes, in particular CYP2D6, CYP2C19, CYP2C9, CYP1B1, CYP1A2 and XO, with special emphasis on the Ethiopian population. READ MORE