Search for dissertations about: "Elias Johansson"

Found 4 swedish dissertations containing the words Elias Johansson.

  2. 1. Carotid stenosis

    Author : Elias Johansson; Per Wester; Conny Arnerlöv; Arne Lindgren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carotid stenosis; Risk; Recurrence; Stroke; TIA; Near-occlusion; Carotid Endarterectomy; Delay; Panoramic Radiographs; Cardiovascular medicine; Kardiovaskulär medicin; Neurology; Neurologi; Internal Medicine; invärtesmedicin; neurologi; Neurology; odontologi; Odontology;

    Abstract : Carotid stenosis is one of several causes of ischemic stroke and entails a high risk of ischemic stroke recurrence. Removal of a carotid stenosis by carotid endarterectomy results in a risk reduction for ischemic stroke, but the magnitude of risk reduction depends on several factors. READ MORE

  4. 2. Functional and structural properties of eukaryotic DNA polymerase epsilon

    Author : Olga Chilkova; Erik Johansson; Per Elias; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; eukaryotic DNA replication; DNA polymerase epsilon; protein-DNA interaction; Biochemistry; Biokemi;

    Abstract : In eukaryotes there are three DNA polymerases which are essential for the replication of chromosomal DNA: DNA polymerase alpha (Pol alpha), DNA polymerase delta (Pol delta) and DNA polymerase epsilon (Pol epsilon). In vitro studies of viral DNA replication showed that Pol alpha and Pol delta are sufficient for DNA replication on both leading and lagging DNA strands, thus leaving the function of Pol epsilon unknown. READ MORE

  5. 3. Structural and biochemical basis for the high fidelity and processivity of DNA polymerase ε

    Author : Rais Ahmad Ganai; Erik Johansson; Per Elias; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA polymerase ε; Crystal structure; P domain; Pre-steady state kinetics; β-hairpin loop; Primer switching; Strand displacement; biokemi; Biochemistry;

    Abstract : DNA polymerase epsilon (Pol ε) is a multi-subunit B-family DNA polymerase that is involved in leading strand DNA replication in eukaryotes. DNA Pol ε in yeast consists of four subunits, Pol2, Dpb2, Dpb3, and Dpb4. Pol2 is the catalytic subunit and Dpb2, Dpb3, and Dpb4 are the accessory subunits. READ MORE

  6. 4. Biochemical analysis of Pfh1, the essential Pif1 family helicase in Schizosaccharomyces pombe

    Author : Jani B. Mohammad; Nasim Sabouri; Erik Johansson; Per Elias; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; G4; Pfh1; Genome integrity; helicase; medicinsk biokemi; Medical Biochemistry;

    Abstract : DNA stores the genetic information of all living organisms, and this information needs to be copied accurately and passed on to each daughter cell when a cell divides. However, the DNA replication machinery often meets obstacles in the genome that cause fork pausing and might result in DNA damage. READ MORE