Search for dissertations about: "Elodie L Plan"

Found 1 swedish dissertation containing the words Elodie L Plan.

2. 1. Pharmacometric Methods and Novel Models for Discrete Data

   Author : Elodie L Plan; Mats O Karlsson; Laura Sargentini-Maier; Armel Stockis; Christian Laveille; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacodynamics; disease progression; modelling; discrete data; count; ordered categorical; repeated time-to-event; RTTCE; RCEpT; NONMEM; FOCE; LAPLACE; SAEM; AGQ; pain scores; epilepsy seizures; gastroesophageal symptoms; statistical power; simulations; diagnostics; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Abstract : Pharmacodynamic processes and disease progression are increasingly characterized with pharmacometric models. However, modelling options for discrete-type responses remain limited, although these response variables are commonly encountered clinical endpoints. Types of data defined as discrete data are generally ordinal, e.g. READ MORE