Search for dissertations about: "Elvar Theodorsson"

Showing result 1 - 5 of 9 swedish dissertations containing the words Elvar Theodorsson.

  1. 1. Estrogen-inducible neuropeptides in the rat brain: role in focal ischemic lesions

    Author : Annette Theodorsson; Elvar Theodorsson; A: Langmoen; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Estrogen; neuropeptides; galanin; cerebral ischemia; middle cerebral artery occlusion; Neurochemistry; Neurokemi;

    Abstract : Sex steroids in general and estrogens in particular – in addition to their effects on the reproductive organs – affect a large number of crucial bodily functions, including “higher” brain functions.Neuropeptides constitute the phylogenetically oldest neurotransmitter system and are currently thought to act mainly during stress, disease or injury. READ MORE

  2. 2. Focal ischemic reperfusion stroke model in rats and the role of galanin

    Author : Lovisa Holm; Annette Theodorsson; Elvar Theodorsson; Tomas Hökfelt; Yanlin Wang-Fischer; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Stroke is the third most common cause for mortality in industrialised countries and amongst the major causes of long- time morbidity. While the mortality due to myocardial infarction has been dramatically reduced during the last 10-15 years, mortality due to stroke remains almost the same, despite the fact that the two share similar basic pathogenic mechanisms including atherosclerosis, hypertension and diabetes. READ MORE

  3. 3. Challenges in experimental stroke research : The 17β-estradiol example

    Author : Edvin Ingberg; Jakob Ström; Elvar Theodorsson; Annette Theodorsson; Tomas Deierborg; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Ischemic stroke causes millions of deaths around the world each year, and surviving patients often suffer from long-term disability. Hundreds of promising drug candidates have been identified in animal models, but the clinical trials have repeatedly failed. Lack of methodological quality in the animal studies, e.g. READ MORE

  4. 4. The dose-dependent effects of estrogens on ischemic stroke

    Author : Jakob Ström; Annette Theodorsson; Elvar Theodorsson; Mats Hammar; Torbjörn Bäckström; Linköpings universitet; []
    Keywords : ;

    Abstract : Estrogens are a group of female sex hormones that in addition to central roles in reproductive functions also have profound impact on for example brain development, blood vessels, bone tissue, metabolism and the immune system. The dominant endogenous production sites for estrogens in females are the ovaries and adipose tissue, while exogenous sources include combined contraceptive hormone treatments and menopausal hormone therapy. READ MORE

  5. 5. Thrombin generation in different cohorts : Evaluation of the haemostatic potential

    Author : Roza Chaireti; Tomas Lindahl; Elvar Theodorsson; Sven Almer; Per Morten Sandset; Linköpings universitet; []
    Keywords : ;

    Abstract : The aim of this thesis is to evaluate thrombin generation in patients with thrombophilia (Paper I), in patients with venous thromboembolism (Paper II), in healthy women during the menstrual cycle (Paper III), in patients with liver disease (Paper IV) and in patients with mild deficiency of factor VII (Paper V).For this purpose, thrombin generation was measured in platelet poor plasma by the calibrated automated thrombogram (CAT®) assay. READ MORE