Search for dissertations about: "Emelie Wallerstedt"

Found 1 swedish dissertation containing the words Emelie Wallerstedt.

2. 1. Regulation of IL-6-signaling and inflammatory response – Role of insulin, FOXO1 and PKCδ

   Author : Emelie Wallerstedt; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2-Diabetes; inflammation; obesity; IL-6; STAT3; PKCδ; FOXO1;

   Abstract : The aim of this thesis was to investigate if and how insulin antagonizes interleukin-6 (IL-6)-signaling and action using both 3T3-L1 mouse adipocytes (Paper I) and HepG2 human hepatocytes (Paper III). We also investigated the importance of PKCδ in 3T3-L1 adipocytes and mouse embryonic fibroblasts (MEFs) lacking protein kinase C-δ (PKCδ-/-) (Paper II). READ MORE