Search for dissertations about: "Emily Carol Hodges"

Found 1 swedish dissertation containing the words Emily Carol Hodges.

2. 1. High resolution genomic tools for the discovery of protein function in mammalian cells

   Author : Emily Carol Hodges; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cell-based assays; overexpression; RNAi; BC2; C3F; Taxol;

   Abstract : The work described in this thesis emphasizes the development of cell-based strategies with increased throughput design that enable rapid biological discovery through direct investigation of protein function. Each of the works represented in this thesis are unified by the common premise that genetic perturbations, through loss or gain-of-function, in cell-based models may serve as an entry point for assigning biological roles to uncharacterized genes and their gene products. READ MORE